Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.56 |
| ▸ | RAD52 | P43351 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17039155 | 0.93 | NAAA (0.46) | NAAARAD52NPSR1PRSS1PRSS2 | |
| SCHEMBL16299753 | 0.82 | PRSS1 (0.64) | NAAARAD52NPSR1PRSS1PRSS2 | |
| SCHEMBL16299767 | 0.82 | PRSS1 (0.64) | NAAARAD52NPSR1PRSS1PRSS2 | |
| SCHEMBL16013207 | 0.82 | ALOX5 (0.33) | NAAARAD52NPSR1 | |
| SCHEMBL17411107 | 0.79 | CYP1A2 (0.33) | PRSS1PRSS2PRSS3HTR2C | |
| SCHEMBL8379908 | 0.78 | NAAA (0.64) | NAAARAD52NPSR1PRSS1PRSS2 | |
| SCHEMBL8642295 | 0.78 | NAAA (0.64) | NAAARAD52NPSR1PRSS1PRSS2 | |
| SCHEMBL14682838 | 0.78 | ALDH1A1 (0.35) | NAAARAD52NPSR1PRSS1PRSS2 | |
| SCHEMBL25808991 | 0.77 | ALDH1A1 (0.47) | DGKATSHRALDH1A1 | |
| SCHEMBL8642771 | 0.76 | NAAA (0.61) | NAAARAD52NPSR1PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023212650-A1 | NEXT GENERATION DIPROVOCIMS THAT ACTIVATE THE INNATE AND ADAPTIVE IMMUNE RESPONSE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-11-02 | — | — | WO | disclosed |