Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 5/20 | 0.35 |
| ▸ | FABP3 | P05413 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | EED | O75530 | 3/20 | 0.33 |
| ▸ | RBBP4 | Q09028 | 3/20 | 0.33 |
| ▸ | SUZ12 | Q15022 | 3/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.33 |
| ▸ | AEBP2 | Q6ZN18 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | GNRHR | P30968 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20344816 | 0.89 | APP (0.33) | FABP4FABP3NPC1CLK1RAB9A | |
| SCHEMBL17039278 | 0.84 | FABP4 (0.41) | FABP4FABP3GNRHRGRM5 | |
| SCHEMBL20344817 | 0.83 | NR1I2 (0.36) | FABP4FABP3 | |
| SCHEMBL18364988 | 0.83 | NR1I2 (0.36) | FABP4FABP3 | |
| SCHEMBL17029028 | 0.82 | NR1I2 (0.42) | FABP4 | |
| SCHEMBL17029056 | 0.82 | NR1I2 (0.42) | FABP4 | |
| SCHEMBL17039255 | 0.81 | CLK1 (0.40) | FABP4FABP3NPC1CLK1RAB9A | |
| SCHEMBL20344807 | 0.81 | P2RX7 (0.33) | P2RX7 | |
| SCHEMBL20344808 | 0.80 | GNRHR (0.35) | FABP4FABP3NPC1RAB9AMAPT | |
| SCHEMBL20344786 | 0.78 | P2RX7 (0.33) | MAPTP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015126765-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-08-27 | — | — | WO | disclosed |