Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19455426 | 0.91 | GAA (0.45) | SLC6A5GAATSHRCYP3A4HPGD | |
| SCHEMBL3149173 | 0.90 | TSHR (0.53) | SLC6A5TSHRMEN1ALDH1A1RECQL | |
| SCHEMBL22807634 | 0.89 | SLC6A5 (0.47) | SLC6A5GAAFAAHCA12CA1 | |
| SCHEMBL13035788 | 0.89 | GLP1R (0.49) | SLC6A5GAATSHRMEN1ALDH1A1 | |
| SCHEMBL16307723 | 0.87 | SLC6A5 (0.46) | SLC6A5GAATSHRLMNAPAOX | |
| SCHEMBL12474155 | 0.87 | FAAH (0.46) | SLC6A5GAATSHRFAAHCYP3A4 | |
| SCHEMBL8524743 | 0.87 | FAAH (0.46) | SLC6A5GAATSHRFAAHCYP3A4 | |
| SCHEMBL12125335 | 0.87 | SLC6A5 (0.59) | SLC6A5FAAH | |
| SCHEMBL26433553 | 0.87 | TSHR (0.43) | SLC6A5GAATSHRMEN1LMNA | |
| SCHEMBL17039863 | 0.86 | SLC6A5 (0.59) | SLC6A5MEN1ALDH1A1PLGLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11286285-B2 | Modified biotin, streptavidin mutant, and usage of them | SAVID THERAPEUTICS INC. (JP) | 2022-03-29 | — | — | US | disclosed |
| US-11161884-B2 | Modified biotin, streptavidin mutant, and usage of them | SAVID THERAPEUTICS INC. (JP) | 2021-11-02 | — | — | US | disclosed |
| US-11124549-B2 | — | — | 2021-09-21 | — | — | US | disclosed |
| EP-3842440-A2 | MODIFIED BIOTIN, STREPTAVIDIN MUTANT, AND USAGE OF THEM | Savid Therapeutics Inc. (JP) | 2021-06-30 | — | — | EP | disclosed |
| EP-3109252-B1 | MODIFIED BIOTIN, STREPTAVIDIN MUTANT, AND USAGE OF THEM | SAVID THERAPEUTICS INC (JP) | 2020-12-30 | — | — | EP | disclosed |
| US-20170145063-A1 | MODIFIED BIOTIN, STREPTAVIDIN MUTANT, AND USAGE OF THEM | SAVID THERAPEUTICS INC. (JP) | 2017-05-25 | — | — | US | disclosed |
| US-20170145063-A1 | MODIFIED BIOTIN, STREPTAVIDIN MUTANT, AND USAGE OF THEM | SAVID THERAPEUTICS INC. (JP) | 2017-05-25 | — | — | US | disclosed |
| WO-2015125820-A1 | BIOTIN VARIANT, STREPTAVIDIN MUTANT, AND USES THEREOF | サヴィッド・セラピューティックス株式会社 | 2015-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170145063-A1 | MODIFIED BIOTIN, STREPTAVIDIN MUTANT, AND USAGE OF THEM | BTD, HLCS, BROX | SLC6A5 2069/4885GAA 4187/4885TSHR 646/4885 |
| US-11124549-B2 | — | BTD, HLCS, BROX | SLC6A5 1191/4885GAA 3277/4885TSHR 1555/4885 |
| US-11161884-B2 | Modified biotin, streptavidin mutant, and usage of them | BTD, HLCS, BROX | SLC6A5 1137/4885GAA 3712/4885TSHR 1853/4885 |
| US-11286285-B2 | Modified biotin, streptavidin mutant, and usage of them | BTD, HLCS, BROX | SLC6A5 2069/4885GAA 4187/4885TSHR 646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.