SCHEMBL17039702

SCHEMBL17039702

N=C1N[C@H]2[C@H](CS[C@H]2CCCCC(=O)NCCOCCNC(=O)c2cc(NC(=O)NCCOCCOCCN)cc(C(=O)NCCOCCNC(=O)CCCC[C@@H]3SC[C@@H]4NC(=N)N[C@@H]43)c2)N1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ PKM P14618 2/20 0.49
▸ PRSS1 P07477 3/20 0.47
▸ PRSS2 P07478 3/20 0.47
▸ PRSS3 P35030 3/20 0.47
▸ TPSAB1 Q15661 3/20 0.47
▸ F2 P00734 2/20 0.47
▸ L3MBTL3 Q96JM7 1/20 0.46
▸ FOLH1 Q04609 6/20 0.44
▸ NSD2 O96028 1/20 0.44
▸ NSD3 Q9BZ95 1/20 0.44
▸ PLG P00747 2/20 0.44
▸ DPP8 Q6V1X1 2/20 0.43
▸ DPP9 Q86TI2 2/20 0.43
▸ LY6K Q17RY6 1/20 0.41
▸ KDM1A O60341 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL18334640 0.95 PKM (0.45) PKMPRSS1PRSS2PRSS3TPSAB1
SCHEMBL18876552 0.92 PKM (0.49) PKMPRSS1PRSS2PRSS3TPSAB1
SCHEMBL23836697 0.92 PKM (0.50) PKMPRSS1PRSS2PRSS3TPSAB1
SCHEMBL17039654 0.92 PKM (0.50) PKMPRSS1PRSS2PRSS3TPSAB1
SCHEMBL22994326 0.92 PKM (0.50) PKMPRSS1PRSS2PRSS3TPSAB1
SCHEMBL25923982 0.92 PKM (0.50) PKMPRSS1PRSS2PRSS3TPSAB1
SCHEMBL17039659 0.89 FOLH1 (0.46) PKMPRSS1PRSS2PRSS3TPSAB1
Trifluoroacetic Acid SCHEMBL22828936 0.89 PKM (0.46) PKMPRSS1PRSS2PRSS3TPSAB1
SCHEMBL22840822 0.88 L3MBTL3 (0.45) PKMPRSS1PRSS2PRSS3TPSAB1
SCHEMBL17039703 0.88 L3MBTL3 (0.45) PKMPRSS1PRSS2PRSS3TPSAB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11286285-B2 Modified biotin, streptavidin mutant, and usage of them SAVID THERAPEUTICS INC. (JP) 2022-03-29 — — US disclosed
US-11161884-B2 Modified biotin, streptavidin mutant, and usage of them SAVID THERAPEUTICS INC. (JP) 2021-11-02 — — US disclosed
US-11124549-B2 — — 2021-09-21 — — US disclosed
EP-3842440-A2 MODIFIED BIOTIN, STREPTAVIDIN MUTANT, AND USAGE OF THEM Savid Therapeutics Inc. (JP) 2021-06-30 — — EP disclosed
EP-3109252-B1 MODIFIED BIOTIN, STREPTAVIDIN MUTANT, AND USAGE OF THEM SAVID THERAPEUTICS INC (JP) 2020-12-30 — — EP disclosed
US-20190382435-A1 CLEARING AGENT SAVID THERAPEUTICS INC. (JP) 2019-12-19 — — US disclosed
US-20170145063-A1 MODIFIED BIOTIN, STREPTAVIDIN MUTANT, AND USAGE OF THEM SAVID THERAPEUTICS INC. (JP) 2017-05-25 — — US disclosed
WO-2015125820-A1 BIOTIN VARIANT, STREPTAVIDIN MUTANT, AND USES THEREOF サヴィッド・セラピューティックス株式会社 2015-08-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170145063-A1 MODIFIED BIOTIN, STREPTAVIDIN MUTANT, AND USAGE OF THEM BTD, HLCS, BROX PKM 4647/4885PRSS1 1862/4885PRSS2 1718/4885
US-11124549-B2 — BTD, HLCS, BROX PKM 4769/4885PRSS1 1346/4885PRSS2 1481/4885
US-11161884-B2 Modified biotin, streptavidin mutant, and usage of them BTD, HLCS, BROX PKM 4765/4885PRSS1 1074/4885PRSS2 1145/4885
US-20190382435-A1 CLEARING AGENT MAN2B1, MAN2B2, ESYT1 PKM 4490/4885PRSS1 894/4885PRSS2 851/4885
US-11286285-B2 Modified biotin, streptavidin mutant, and usage of them BTD, HLCS, BROX PKM 4647/4885PRSS1 1862/4885PRSS2 1718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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