SCHEMBL1704404

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3324258	0.75	CA2 (0.59)	KMT2ACA2CA1
	SCHEMBL7671756	0.70	HDAC6 (0.55)	HTTRAB9AALDH1A1SMN1; SMN2HPGD
	SCHEMBL1704405	0.69	HDAC3 (0.60)	ALDH1A1NAMPTKMT2ASMN1; SMN2HDAC8
	SCHEMBL12640546	0.68	RAB9A (0.43)	HTTRAB9AALDH1A1CNR2SMN1; SMN2
	SCHEMBL13579010	0.67	HDAC3 (0.38)	HTTALDH1A1KMT2ASMN1; SMN2HPGD
	SCHEMBL12640590	0.67	HTT (0.47)	HTTALDH1A1MAPT
	SCHEMBL1176735	0.66	LMNA (0.45)	HTTRAB9AKMT2ASMN1; SMN2NPC1
	SCHEMBL5640360	0.66	MAPT (0.50)	HTTRAB9AALDH1A1MEN1KMT2A
	SCHEMBL5536709	0.65	HPGD (0.59)	RAB9AALDH1A1MEN1KMT2ASMN1; SMN2
	SCHEMBL10147900	0.65	ALDH1A1 (0.55)	HTTRAB9AALDH1A1CNR2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.