SCHEMBL17044686

SCHEMBL17044686

C=COCC(=C)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.44
MAOB P27338 6/20 0.44
AKT1 P31749 2/20 0.39
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
KMT2A Q03164 1/20 0.37
CDK1 P06493 1/20 0.36
CCNB1 P14635 1/20 0.36
MGMT P16455 1/20 0.36
CCNA2 P20248 1/20 0.36
CDK2 P24941 1/20 0.36
CCNA1 P78396 1/20 0.36
NFE2L2 Q16236 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL58239 0.78 MAOA (0.47) MAOAMAOBAKT1
SCHEMBL3752087 0.78 MAOA (0.50) MAOAMAOBMEN1LMNAKMT2A
SCHEMBL5245553 0.78 MAPT (0.50) AKT1MEN1LMNAKMT2A
SCHEMBL4828670 0.76 MAOA (0.41) MAOAMAOBAKT1LMNACDK1
SCHEMBL9330920 0.76 MAOA (0.48) MAOAMAOBMEN1LMNAKMT2A
SCHEMBL17594174 0.73 THRB (0.51) MAOAMAOBAKT1LMNAKMT2A
Hydrochloric Acid SCHEMBL5694868 0.72 MAOA (0.53) MAOAMAOBKMT2ACDK1CCNB1
SCHEMBL9310259 0.72 ALOX15 (0.54) MAOAMAOBMEN1KMT2ACDK1
SCHEMBL30680 0.71 MAOA (0.48) MAOAMAOBAKT1LMNA
SCHEMBL194628 0.71 ALDH1A1 (0.44) MAOAMAOBMEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240191087-A1 WATER DISPERSIBLE SULFONATED THERMOPLASTIC COPOLYMER FOR USE IN ADDITIVE MANUFACTURING STRATASYS INC (US) 2024-06-13 US disclosed
US-11939480-B2 Water dispersible sulfonated thermoplastic copolymer for use in additive manufacturing STRATASYS, INC. (US) 2024-03-26 US disclosed
WO-2023171597-A1 HIGH-PURITY 4-(2-BROMOETHYL)BENZENESULFONIC ACID, HIGH-PURITY STYRENESULFONIC ACIDS DERIVED THEREFROM AND POLYMERS THEREOF, AND METHODS FOR PRODUCING SAME 東ソー・ファインケム株式会社 2023-09-14 WO disclosed
US-11459410-B2 High-purity amphipathic arylsulfonic acid amine salt vinyl monomer and copolymer thereof TOSOH FINECHEM CORPORATION (JP) 2022-10-04 US disclosed
CN-110997631-B High purity amphiphilic arylsulfonic acid amine salt vinyl monomers and (co) polymers thereof 东曹精细化工株式会社 2022-07-15 CN disclosed
US-11220062-B2 Water-dispersible thermoplastic material comprising sulfonated copolymer for use in additive manufacturing STRATASYS, INC. (US) 2022-01-11 US disclosed
US-20210348010-A1 WATER DISPERSIBLE SULFONATED THERMOPLASTIC COPOLYMER FOR USE IN ADDITIVE MANUFACTURING STRATASYS, INC. 2021-11-11 US disclosed
EP-3864093-A1 WATER DISPERSIBLE SULFONATED THERMOPLASTIC COPOLYMER FOR USE IN ADDITIVE MANUFACTURING Stratasys, Inc. (US) 2021-08-18 EP disclosed
US-20210237364-A1 METHOD OF TREATING A DISPERSION OF SULFOPOLYMER STRATASYS, INC. 2021-08-05 US disclosed
US-10982043-B2 Recycling and reuse of sulfonated polymer material in additive manufacturing STRATASYS, INC. (US) 2021-04-20 US disclosed
EP-3694939-A1 WATER-DISPERSIBLE THERMOPLASTIC MATERIAL COMPRISING SULFONATED COPOLYMER FOR USE IN ADDITIVE MANUFACTURING Stratasys, Inc. (US) 2020-08-19 EP disclosed
US-20200207025-A1 WATER-DISPERSIBLE THERMOPLASTIC MATERIAL COMPRISING SULFONATED COPOLYMER FOR USE IN ADDITIVE MANUFACTURING STRATASYS, INC. 2020-07-02 US disclosed
EP-3666753-A1 HIGH-PURITY AMPHIPATHIC ARYLSULFONIC ACID AMINE SALT VINYL MONOMER AND COPOLYMER THEREOF Tosoh Finechem Corporation (JP) 2020-06-17 EP disclosed
US-20200172643-A1 HIGH-PURITY AMPHIPATHIC ARYLSULFONIC ACID AMINE SALT VINYL MONOMER AND COPOLYMER THEREOF TOSOH FINECHEM CORPORATION (JP) 2020-06-04 US disclosed
CN-104736516-B Sodium p-styrenesulfonate, process for producing the same, sodium p-styrenesulfonate, dispersant using the same, and synthetic paste for dressing 东曹精细化工株式会社 2019-11-08 CN disclosed
WO-2019075107-A1 WATER-DISPERSIBLE THERMOPLASTIC MATERIAL COMPRISING SULFONATED COPOLYMER FOR USE IN ADDITIVE MANUFACTURING STRATASYS, INC. (US) 2019-04-18 WO disclosed
US-20180030234-A1 RECYCLING AND REUSE OF SULFONATED POLYMER MATERIAL IN ADDITIVE MANUFACTURING STRATASYS, INC. 2018-02-01 US disclosed
US-9505713-B2 High-purity sodium p-styrenesulfonate with excellent hue, method for producing the same, poly(sodium p-styrenesulfonate) with excellent hue using the same, and dispersant and synthetic starch for clothing finishing using the poly(sodium p-styrenesulfonate) TOSOH ORGANIC CHEMICAL CO., LTD (JP) 2016-11-29 US disclosed
CN-103958552-B The manufacture method of high-purity sodium p styrene sulfonate and the manufacture method of kayexalate 东曹有机化学株式会社 2016-11-16 CN disclosed
US-20150246876-A1 HIGH-PURITY SODIUM P-STYRENESULFONATE WITH EXCELLENT HUE, METHOD FOR PRODUCING THE SAME, POLY (SODIUM P-STYRENESULFONATE) WITH EXCELLENT HUE USING THE SAME, AND DISPERSANT AND SYNTHETIC STARCH FOR CLOTHING FINISHING USING THE POLY ( SODIUM P-STYRENESULFONATE) TOSOH ORGANIC CHEMICAL CO., LTD. (JP) 2015-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11459410-B2 High-purity amphipathic arylsulfonic acid amine salt vinyl monomer and copolymer thereof SLC7A1, ARSA, STS MAOA 2316/4885MAOB 2694/4885AKT1 1965/4885
US-20200172643-A1 HIGH-PURITY AMPHIPATHIC ARYLSULFONIC ACID AMINE SALT VINYL MONOMER AND COPOLYMER THEREOF SLC7A1, ARSA, STS MAOA 2316/4885MAOB 2694/4885AKT1 1965/4885
US-20150246876-A1 HIGH-PURITY SODIUM P-STYRENESULFONATE WITH EXCELLENT HUE, METHOD FOR PRODUCING THE SAME, POLY (SODIUM P-STYRENESULFONATE) WITH EXCELLENT HUE USING THE SAME, AND DISPERSANT AND SYNTHETIC STARCH FOR CLOTHING FINISHING USING THE POLY ( SODIUM P-STYRENESULFONATE) HPSE, STS, TST MAOA 2981/4885MAOB 1155/4885AKT1 2223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.