SCHEMBL17045229

SCHEMBL17045229

CNC(=O)OC(=O)NC[C@@H](Cc1ccccc1)N(C)C

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 18/20 0.57
OPRK1 P41145 11/20 0.55
OPRD1 P41143 9/20 0.55
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17045287 0.79 OPRD1 (0.46) OPRM1OPRK1OPRD1
SCHEMBL17045286 0.79 OPRD1 (0.46) OPRM1OPRK1OPRD1
SCHEMBL17045284 0.79 OPRD1 (0.46) OPRM1OPRK1OPRD1
SCHEMBL28020779 0.75 CYP1A2 (0.51) ALDH1A1
SCHEMBL7396098 0.74 OPRK1 (0.64) OPRM1OPRK1OPRD1ALDH1A1LMNA
SCHEMBL7396097 0.74 OPRK1 (0.64) OPRM1OPRK1OPRD1ALDH1A1LMNA
SCHEMBL5666326 0.73 OPRM1 (0.48) OPRM1OPRK1OPRD1ALDH1A1LMNA
SCHEMBL23375742 0.71 OPRM1 (0.70) OPRM1OPRK1OPRD1
SCHEMBL18375268 0.71 OPRM1 (1.00) OPRM1OPRK1OPRD1
SCHEMBL18375504 0.71 OPRM1 (1.00) OPRM1OPRK1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230218562-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-07-13 US disclosed
US-20210113514-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS., LTD. 2021-04-22 US disclosed
US-10888542-B2 Aminocarbonylcarbamate compounds SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-01-12 US disclosed
US-20200046674-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2020-02-13 US disclosed
US-20190247356-A1 Aminocarbonylcarbamate Compounds SK BIOPHARMACEUTICALS CO., LTD. 2019-08-15 US disclosed
US-10314808-B2 Aminocarbonylcarbamate compounds SK BIOPHARMACEUTICALS CO., LTD. (KR) 2019-06-11 US disclosed
US-20180085337-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2018-03-29 US disclosed
US-9833432-B2 Aminocarbonylcarbamate compounds SK BIOPHARMACEUTICALS CO., LTD. (KR) 2017-12-05 US disclosed
EP-3110792-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK Biopharmaceuticals Co., Ltd. (KR) 2017-01-04 EP disclosed
US-20160303067-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. 2016-10-20 US disclosed
US-9403761-B2 Aminocarbonylcarbamate compounds SK BIOPHARMACEUTICALS CO., LTD. (KR) 2016-08-02 US disclosed
WO-2015130121-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2015-09-03 WO disclosed
US-20150246874-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2015-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190247356-A1 Aminocarbonylcarbamate Compounds SLC6A3, SLC6A2, SLC6A4 OPRM1 51/4885OPRK1 8/4885OPRD1 32/4885
US-20150246874-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 OPRM1 51/4885OPRK1 8/4885OPRD1 32/4885
US-10888542-B2 Aminocarbonylcarbamate compounds SLC6A3, SLC6A2, SLC6A4 OPRM1 51/4885OPRK1 8/4885OPRD1 32/4885
US-20160303067-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 OPRM1 51/4885OPRK1 8/4885OPRD1 32/4885
US-20180085337-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 OPRM1 51/4885OPRK1 8/4885OPRD1 32/4885
US-20210113514-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 OPRM1 51/4885OPRK1 8/4885OPRD1 32/4885
US-20200046674-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 OPRM1 51/4885OPRK1 8/4885OPRD1 32/4885
US-20230218562-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 OPRM1 51/4885OPRK1 8/4885OPRD1 32/4885
US-10314808-B2 Aminocarbonylcarbamate compounds SLC6A3, SLC6A2, SLC6A4 OPRM1 51/4885OPRK1 8/4885OPRD1 32/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.