SCHEMBL17045286

SCHEMBL17045286

CNC(=O)OC[C@H](Cc1ccccc1)N(C)C

nearest known ligand 0.61

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 8/20 0.46
OPRK1 P41145 8/20 0.46
OPRM1 P35372 7/20 0.46
CYP1A2 P05177 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17045284 1.00 OPRD1 (0.46) OPRD1OPRK1OPRM1CYP1A2
SCHEMBL17045287 1.00 OPRD1 (0.46) OPRD1OPRK1OPRM1CYP1A2
SCHEMBL17059055 0.85 OPRM1 (0.43) OPRD1OPRK1OPRM1
SCHEMBL30175767 0.85 OPRM1 (0.43) OPRD1OPRK1OPRM1
SCHEMBL30175803 0.82 OPRM1 (0.44) OPRD1OPRK1OPRM1
SCHEMBL30175831 0.82 OPRM1 (0.44) OPRD1OPRK1OPRM1
SCHEMBL17045229 0.79 OPRM1 (0.57) OPRD1OPRK1OPRM1
SCHEMBL17045283 0.79 MMP2 (0.51) CYP1A2
SCHEMBL11947651 0.79 MMP2 (0.51) CYP1A2
SCHEMBL17045285 0.79 MMP2 (0.51) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210113514-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS., LTD. 2021-04-22 US disclosed
US-10888542-B2 Aminocarbonylcarbamate compounds SK BIOPHARMACEUTICALS CO., LTD. (KR) 2021-01-12 US disclosed
US-20200046674-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2020-02-13 US disclosed
EP-3110792-B1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO LTD (KR) 2019-09-04 EP disclosed
US-20190247356-A1 Aminocarbonylcarbamate Compounds SK BIOPHARMACEUTICALS CO., LTD. 2019-08-15 US disclosed
US-10314808-B2 Aminocarbonylcarbamate compounds SK BIOPHARMACEUTICALS CO., LTD. (KR) 2019-06-11 US disclosed
US-20180085337-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2018-03-29 US disclosed
US-9833432-B2 Aminocarbonylcarbamate compounds SK BIOPHARMACEUTICALS CO., LTD. (KR) 2017-12-05 US disclosed
EP-3110792-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK Biopharmaceuticals Co., Ltd. (KR) 2017-01-04 EP disclosed
US-20160303067-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. 2016-10-20 US disclosed
US-9403761-B2 Aminocarbonylcarbamate compounds SK BIOPHARMACEUTICALS CO., LTD. (KR) 2016-08-02 US disclosed
WO-2015130121-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2015-09-03 WO disclosed
US-20150246874-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SK BIOPHARMACEUTICALS CO., LTD. (KR) 2015-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190247356-A1 Aminocarbonylcarbamate Compounds SLC6A3, SLC6A2, SLC6A4 OPRD1 32/4885OPRK1 8/4885OPRM1 51/4885
US-20150246874-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 OPRD1 32/4885OPRK1 8/4885OPRM1 51/4885
US-10888542-B2 Aminocarbonylcarbamate compounds SLC6A3, SLC6A2, SLC6A4 OPRD1 32/4885OPRK1 8/4885OPRM1 51/4885
US-20160303067-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 OPRD1 32/4885OPRK1 8/4885OPRM1 51/4885
US-20180085337-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 OPRD1 32/4885OPRK1 8/4885OPRM1 51/4885
US-20210113514-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 OPRD1 32/4885OPRK1 8/4885OPRM1 51/4885
US-20200046674-A1 AMINOCARBONYLCARBAMATE COMPOUNDS SLC6A3, SLC6A2, SLC6A4 OPRD1 32/4885OPRK1 8/4885OPRM1 51/4885
US-10314808-B2 Aminocarbonylcarbamate compounds SLC6A3, SLC6A2, SLC6A4 OPRD1 32/4885OPRK1 8/4885OPRM1 51/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.