Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170456 | 0.78 | PLAU (0.43) | HSD17B10PLAU | |
| SCHEMBL29504825 | 0.78 | PLAU (0.43) | HSD17B10PLAU | |
| SCHEMBL31312839 | 0.76 | PLAU (0.42) | HSD17B10PLAU | |
| SCHEMBL8827973 | 0.76 | PLAU (0.42) | HSD17B10PLAU | |
| Hydrochloric Acid SCHEMBL10824104 | 0.76 | PLAU (0.42) | HSD17B10PLAU | |
| Benzo[D]Thiazole SCHEMBL8430 | 0.74 | — | — | |
| Benzo[D]Thiazole SCHEMBL10847268 | 0.74 | — | — | |
| Benzo[D]Thiazole SCHEMBL31388426 | 0.74 | — | — | |
| Benzo[D]Thiazole SCHEMBL900814 | 0.74 | ALDH1A1 (1.00) | ALDH1A1HSD17B10SLC6A2SLC6A4SLC6A3 | |
| Benzo[D]Thiazole SCHEMBL451685 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110286973-A1 | METHODS FOR INTRODUCING HETEROLOGOUS CELLS INTO FISH | PHYLONIX PHARMACEUTICALS, INC. (US) | 2011-11-24 | — | — | US | claimed |
| US-7838726-B2 | Methods for introducing heterologous cells into fish | PHYLONIX PHARMACEUTICALS, INC. (US) | 2010-11-23 | — | — | US | claimed |
| US-20070130632-A1 | METHODS FOR INTRODUCING HETEROLOGOUS CELLS INTO FISH | SERBEDZIJA GEORGE N | 2007-06-07 | — | — | US | claimed |
| US-20020025297-A1 | Methods of screening agents for activity using teleosts | SERBEDZIJA GEORGE N (US) | 2002-02-28 | — | — | US | claimed |
| US-6299858-B1 | CONTACTING LIVING TELEOST POST 12-HOURS OF DEVELOPMENT WITH DYE HAVING AFFINITY FOR DEAD CELLS AND STAINS DEAD CELLS; ADMINISTERING AGENT TO LIVING TELEOST; DETECTING STAINING OF DEAD CELLS WITH DYE IN SPECIFIC TISSUE OR ORGAN; COMPARING | PHYLONIX PHARMACEUTICALS, INC. | 2001-10-09 | — | — | US | claimed |
| EP-1066402-A4 | METHODS OF SCREENING AGENTS FOR ACTIVITY USING TELEOSTS | PHYLONIX PHARMACEUTICALS INC (US) | 2001-06-13 | — | — | EP | claimed |
| EP-1066402-A1 | METHODS OF SCREENING AGENTS FOR ACTIVITY USING TELEOSTS | Phylonix Pharmaceuticals Inc. (US) | 2001-01-10 | — | — | EP | claimed |
| WO-1999042606-A1 | METHODS OF SCREENING AGENTS FOR ACTIVITY USING TELEOSTS | PHYLONIX PHARMACEUTICALS, INC. (US) | 1999-08-26 | — | — | WO | claimed |
| US-8993834-B2 | Methods of screening agents for activity using teleosts | PHYLONIX PHARMACEUTICALS, INC. (US) | 2015-03-31 | — | — | US | disclosed |
| US-8741592-B2 | Methods of screening an agent for an activity in an isolated eye of a teleost | PHYLONIX PHARMACEUTICALS, INC. (US) | 2014-06-03 | — | — | US | disclosed |
| US-20130318642-A1 | Methods of Screening Agents for Activity Using Teleosts | PHYLONIX PHARMACEUTICALS, INC. | 2013-11-28 | — | — | US | disclosed |
| US-20130281320-A1 | Methods of Screening an Agent for an Activity in an Isolated Eye of a Teleost | PHYLONIX PHARMACEUTICALS, INC. | 2013-10-24 | — | — | US | disclosed |
| US-8367364-B2 | Methods of screening an agent for an activity in an isolated eye of a teleost | PHYLONIX PHARMACEUTICALS, INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-20120317663-A1 | METHODS OF SCREENING AGENTS FOR ACTIVITY USING TELEOSTS | PHYLONIX PHARMACEUTICALS, INC. (US) | 2012-12-13 | — | — | US | disclosed |
| US-5707808-A | Optical selection and collection of DNA fragments | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-01-13 | — | — | US | disclosed |
| WO-1997002482-A1 | VOLUMETRIC CELL QUANTIFICATION METHOD AND SYSTEM | BIOMETRIC IMAGING, INC. (US) | 1997-01-23 | — | — | WO | disclosed |
| US-5554502-A | QUANTATITIVE | HITACHI CHEMICAL CO. LTD. (JP) | 1996-09-10 | — | — | US | disclosed |
| US-5545528-A | ADDING DYE WHICH COMPLEXES WITH AMPLIFIED NUCLEIC ACID SEQUENCE, OPTICALLY EXCITING WITH VISIBLE LIGHT, DETECTING AND MEASURING LIGHT ENERGY EMITTED TO DETERMINE PRESENCE | HITACHI CHEMICAL RESEARCH CENTER (US) | 1996-08-13 | — | — | US | disclosed |
| US-5534416-A | ANALYZING CELL VIABILITY | MOLECULAR PROBES, INC. (US) | 1996-07-09 | — | — | US | disclosed |
| WO-1995008623-A1 | PROCESS FOR DETERMINING NUCLEASE ACTIVITY | HITACHI CHEMICAL CO., LTD. (JP) | 1995-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020025297-A1 | Methods of screening agents for activity using teleosts | CASP7, BAD, LIPG | ALDH1A1 1661/4885HSD17B10 2762/4885SLC6A2 4324/4885 |
| US-20120317663-A1 | METHODS OF SCREENING AGENTS FOR ACTIVITY USING TELEOSTS | DCX, VEGFA, GMFG | ALDH1A1 2137/4885HSD17B10 3558/4885SLC6A2 3552/4885 |
| US-20130318642-A1 | Methods of Screening Agents for Activity Using Teleosts | DCX, VEGFA, GMFG | ALDH1A1 2137/4885HSD17B10 3558/4885SLC6A2 3552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.