SCHEMBL17049583

SCHEMBL17049583

CNC[C@H](O)c1cc(O)c(O)c(S(=O)(=O)O)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.51
TDP1 Q9NUW8 5/20 0.51
ADRB2 P07550 5/20 0.51
HIF1A Q16665 5/20 0.51
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
ADRB1 P08588 4/20 0.51
ADRB3 P13945 4/20 0.51
ADRA2A P08913 4/20 0.51
ADRA2B P18089 4/20 0.51
ADRA2C P18825 4/20 0.51
MAPT P10636 3/20 0.51
HSD17B10 Q99714 3/20 0.51
TSHR P16473 3/20 0.51
ADRA1A P35348 3/20 0.51
CYP1A2 P05177 2/20 0.51
ALDH1A1 P00352 2/20 0.51
APEX1 P27695 2/20 0.51
DRD1 P21728 2/20 0.51
ADRA1B P35368 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23484536 0.82 KDM4E (0.67) KDM4ETDP1ADRB2HIF1AMEN1
SCHEMBL11743203 0.78 KDM4E (0.57) KDM4ETDP1ADRB2HIF1AMEN1
SCHEMBL26672809 0.77 ADRA2A (0.70) KDM4ETDP1ADRB2HIF1AMEN1
Racepinephrine SCHEMBL9659988 0.75 TDP1 (0.84) KDM4ETDP1ADRB2HIF1AMEN1
Epinephrine SCHEMBL9659298 0.75 TDP1 (0.84) KDM4ETDP1ADRB2HIF1AMEN1
Epinephrine SCHEMBL9659993 0.75 TDP1 (0.84) KDM4ETDP1ADRB2HIF1AMEN1
Epinephrine SCHEMBL7921664 0.75 TDP1 (0.84) KDM4ETDP1ADRB2HIF1AMEN1
Racepinephrine SCHEMBL9659303 0.75 TDP1 (0.84) KDM4ETDP1ADRB2HIF1AMEN1
Racepinephrine SCHEMBL7921668 0.75 TDP1 (0.84) KDM4ETDP1ADRB2HIF1AMEN1
SCHEMBL11670117 0.73 KDM4E (0.64) KDM4ETDP1ADRB2HIF1AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230285326-A1 EPINEPHRINE FORMULATIONS WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL AGENT 2023-09-14 US disclosed
US-20230285326-A1 EPINEPHRINE FORMULATIONS WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL AGENT 2023-09-14 US disclosed
US-20230100523-A1 EPINEPHRINE FORMULATIONS WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL AGENT 2023-03-30 US disclosed
US-11337938-B2 Epinephrine formulations PAR PHARMACEUTICAL, INC. (US) 2022-05-24 US disclosed
US-20200206163-A1 EPINEPHRINE FORMULATIONS WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL AGENT 2020-07-02 US disclosed
US-10624864-B2 Epinephrine formulations PAR PHARMACEUTICAL, INC. (US) 2020-04-21 US disclosed
US-20190151261-A1 EPINEPHRINE FORMULATIONS WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL AGENT 2019-05-23 US disclosed
US-20190105288-A1 EPINEPHRINE FORMULATIONS PAR PHARMACEUTICAL, INC. 2019-04-11 US disclosed
US-20170189352-A1 EPINEPHRINE FORMULATIONS PAR PHARMACEUTICAL, INC. 2017-07-06 US disclosed
US-20170189352-A1 EPINEPHRINE FORMULATIONS PAR PHARMACEUTICAL, INC. 2017-07-06 US disclosed
US-20170165206-A1 EPINEPHRINE FORMULATIONS PAR PHARMACEUTICAL, INC. 2017-06-15 US disclosed
US-20170165206-A1 EPINEPHRINE FORMULATIONS PAR PHARMACEUTICAL, INC. 2017-06-15 US disclosed
WO-2016149028-A2 EPINEPHRINE FORMULATIONS PAR PHARMACEUTICAL, INC. (US) 2016-09-22 WO disclosed
US-20160263059-A1 EPINEPHRINE FORMULATIONS WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL AGENT 2016-09-15 US disclosed
US-20160263059-A1 EPINEPHRINE FORMULATIONS WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL AGENT 2016-09-15 US disclosed
US-9295657-B1 Epinephrine formulations PAR PHARMACEUTICAL, INC. (US) 2016-03-29 US disclosed
US-9295657-B1 Epinephrine formulations PAR PHARMACEUTICAL, INC. (US) 2016-03-29 US disclosed
US-9119876-B1 Epinephrine formulations PAR PHARMACEUTICAL, INC. (US) 2015-09-01 US disclosed
US-9119876-B1 Epinephrine formulations PAR PHARMACEUTICAL, INC. (US) 2015-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190105288-A1 EPINEPHRINE FORMULATIONS ADRA1A, ADRB1, ADRA2C KDM4E 3328/4885TDP1 1290/4885ADRB2 5/4885
US-11337938-B2 Epinephrine formulations ADRA1A, ADRB1, ADRA2C KDM4E 3328/4885TDP1 1290/4885ADRB2 5/4885
US-20160263059-A1 EPINEPHRINE FORMULATIONS ADRA1A, ADRB1, ADRA2C KDM4E 3328/4885TDP1 1290/4885ADRB2 5/4885
US-20190151261-A1 EPINEPHRINE FORMULATIONS ADRA1A, ADRB1, ADRA2C KDM4E 3328/4885TDP1 1290/4885ADRB2 5/4885
US-20170165206-A1 EPINEPHRINE FORMULATIONS ADRA1A, ADRB1, ADRA2C KDM4E 3328/4885TDP1 1290/4885ADRB2 5/4885
US-20230285326-A1 EPINEPHRINE FORMULATIONS ADRA1B, ADRA2C, ADRB1 KDM4E 3695/4885TDP1 2694/4885ADRB2 6/4885
US-10624864-B2 Epinephrine formulations ADRA1A, ADRB1, ADRA2C KDM4E 3328/4885TDP1 1290/4885ADRB2 5/4885
US-20200206163-A1 EPINEPHRINE FORMULATIONS ADRA1A, ADRB1, ADRA2C KDM4E 3328/4885TDP1 1290/4885ADRB2 5/4885
US-20170189352-A1 EPINEPHRINE FORMULATIONS ADRA1A, ADRB1, ADRA2C KDM4E 3328/4885TDP1 1290/4885ADRB2 5/4885
US-20230100523-A1 EPINEPHRINE FORMULATIONS ADRA1A, ADRB1, ADRA2C KDM4E 3328/4885TDP1 1290/4885ADRB2 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.