Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17049860 | 0.85 | SIGMAR1 (0.41) | SIGMAR1GID4HTR1ACHRNA7 | |
| SCHEMBL17049861 | 0.72 | ALDH1A1 (0.34) | MEN1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL12288815 | 0.70 | MET (0.42) | MEN1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL15338767 | 0.69 | ALDH1A1 (0.40) | MEN1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL8849605 | 0.67 | DDB1 (0.53) | SIGMAR1 | |
| SCHEMBL20856099 | 0.67 | GID4 (0.58) | SIGMAR1GID4MEN1ALDH1A1HPGD | |
| SCHEMBL12330396 | 0.67 | NOTUM (0.39) | MEN1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL9675977 | 0.66 | ALDH1A1 (0.49) | MEN1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL14283849 | 0.66 | DRD1 (0.47) | ALDH1A1MAPTHPGD | |
| SCHEMBL11816393 | 0.66 | SMN1; SMN2 (0.45) | SIGMAR1GID4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120836-B2 | Method for preparing transition metal complexes, transition metal complexes prepared using the method, catalyst composition containing the complexes | LG CHEM, LTD. (KR) | 2015-09-01 | — | — | US | disclosed |