Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17049859 | 0.85 | SIGMAR1 (0.37) | SIGMAR1GID4HTR1ACHRNA7 | |
| SCHEMBL17049866 | 0.78 | SRD5A1 (0.41) | SIGMAR1GID4HTR1AADRA1APDPK1 | |
| SCHEMBL2625788 | 0.71 | ALOX12 (0.60) | — | |
| SCHEMBL12680722 | 0.70 | ALOX12 (0.41) | HTR1A | |
| SCHEMBL24358931 | 0.69 | ALOX12 (0.42) | HTR1A | |
| SCHEMBL11837962 | 0.69 | RAB9A (0.47) | — | |
| SCHEMBL20348492 | 0.69 | ALOX12 (0.42) | HTR1A | |
| SCHEMBL2625802 | 0.69 | NOTUM (0.50) | ADRA1A | |
| SCHEMBL3312853 | 0.69 | CES1 (0.44) | HTR1A | |
| SCHEMBL24308956 | 0.69 | ALDH1A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120836-B2 | Method for preparing transition metal complexes, transition metal complexes prepared using the method, catalyst composition containing the complexes | LG CHEM, LTD. (KR) | 2015-09-01 | — | — | US | disclosed |