Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14026066 | 0.89 | ALDH1A1 (0.50) | ALDH1A1MAPTITGA4POLBKDM4E | |
| SCHEMBL4217613 | 0.79 | ALDH1A1 (0.49) | ALDH1A1MAPTITGA4POLBKDM4E | |
| SCHEMBL14045843 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPTITGA4POLBKDM4E | |
| SCHEMBL18994214 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPTITGA4POLBKDM4E | |
| SCHEMBL18663375 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MAPTITGA4POLBKDM4E | |
| SCHEMBL30204529 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MAPTITGA4POLBKDM4E | |
| SCHEMBL29663083 | 0.76 | THRB (0.59) | ALDH1A1MAPTITGA4POLBKDM4E | |
| SCHEMBL3245527 | 0.76 | THRB (0.59) | ALDH1A1MAPTITGA4POLBKDM4E | |
| SCHEMBL9672587 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MAPTITGA4POLBKDM4E | |
| SCHEMBL18748397 | 0.75 | PDK2 (0.46) | THRBTDP1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682060-B2 | Small molecules that induce intrinsic pathway apoptosis | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-06-20 | — | — | US | disclosed |
| US-20170105963-A1 | SMALL MOLECULES THAT INDUCE INTRINSIC PATHWAYS APOPTOSIS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-04-20 | — | — | US | disclosed |
| US-9518150-B2 | Resin composition, stretched film, circularly polarizing plate, and image display device | MITSUBISHI CHEMICAL CORPORATION (JP) | 2016-12-13 | — | — | US | disclosed |
| US-20150247002-A1 | RESIN COMPOSITION, STRETCHED FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2015-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150247002-A1 | RESIN COMPOSITION, STRETCHED FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE | RAD50, RAD54L, PUF60 | ALDH1A1 3155/4885MAPT 1376/4885ITGA4 38/4885 |
| US-20170105963-A1 | SMALL MOLECULES THAT INDUCE INTRINSIC PATHWAYS APOPTOSIS | AIFM1, VDAC1, AFG3L2 | ALDH1A1 3882/4885MAPT 4465/4885ITGA4 2243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.