Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25260720 | 0.84 | RAB9A (0.57) | L3MBTL1SMN1; SMN2THRBNPC1RAB9A | |
| SCHEMBL31114515 | 0.84 | RAB9A (0.57) | L3MBTL1SMN1; SMN2THRBNPC1RAB9A | |
| SCHEMBL29875298 | 0.75 | SMN1; SMN2 (0.61) | TDP1L3MBTL1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL33267 | 0.75 | SMN1; SMN2 (0.61) | TDP1L3MBTL1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL202432 | 0.73 | TDP1 (1.00) | TDP1L3MBTL1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL422166 | 0.72 | CYP1A2 (0.67) | TDP1L3MBTL1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL8332212 | 0.72 | KDM4E (0.58) | TDP1L3MBTL1KMT2ASMN1; SMN2THRB | |
| SCHEMBL29693760 | 0.72 | KDM4E (0.58) | TDP1L3MBTL1KMT2ASMN1; SMN2THRB | |
| SCHEMBL14375385 | 0.72 | TDP1 (0.75) | TDP1L3MBTL1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL8261943 | 0.71 | KMT2A (0.69) | TDP1L3MBTL1KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150246938-A1 | NOVEL OLEFIN DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2015-09-03 | — | — | US | disclosed |
| US-20150246938-A1 | NOVEL OLEFIN DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2015-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246938-A1 | NOVEL OLEFIN DERIVATIVE | ACSS2, ACACB, ACAT2 | TDP1 4691/4885L3MBTL1 3849/4885KMT2A 2738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.