SCHEMBL33267

SCHEMBL33267

Cc1nc2ccc(Br)cc2s1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.61
RAB9A P51151 5/20 0.57
NPC1 O15118 5/20 0.57
ALDH1A1 P00352 3/20 0.57
MAPT P10636 3/20 0.57
TP53 P04637 1/20 0.57
PKM P14618 1/20 0.57
HPGD P15428 1/20 0.57
HSD17B10 Q99714 1/20 0.57
GAA P10253 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
HTT P42858 2/20 0.53
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
DYRK1A Q13627 1/20 0.53
APP P05067 3/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
LDHA P00338 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29875298 1.00 SMN1; SMN2 (0.61) SMN1; SMN2RAB9ANPC1ALDH1A1MAPT
SCHEMBL2174373 0.88 RAB9A (0.50) SMN1; SMN2RAB9ANPC1ALDH1A1MAPT
SCHEMBL202298 0.84 SMN1; SMN2 (0.57) SMN1; SMN2RAB9ANPC1ALDH1A1MAPT
SCHEMBL30181739 0.84 SMN1; SMN2 (0.57) SMN1; SMN2RAB9ANPC1ALDH1A1MAPT
SCHEMBL2098849 0.81 RAB9A (0.56) SMN1; SMN2RAB9ANPC1ALDH1A1MAPT
Iodomethane SCHEMBL27623269 0.81 SMN1; SMN2 (0.53) SMN1; SMN2RAB9ANPC1ALDH1A1MAPT
SCHEMBL84327 0.79 SMN1; SMN2 (0.66) SMN1; SMN2RAB9ANPC1ALDH1A1MAPT
SCHEMBL30542465 0.79 SMN1; SMN2 (0.66) SMN1; SMN2RAB9ANPC1ALDH1A1MAPT
SCHEMBL1849649 0.76 RAB9A (0.51) SMN1; SMN2RAB9ANPC1ALDH1A1MAPT
SCHEMBL141868 0.76 RAB9A (0.51) SMN1; SMN2RAB9ANPC1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118355041-A Method for underwater bonding 汉高股份有限及两合公司 2024-07-16 CN claimed
CN-113045993-A Polishing solution for processing ultra-smooth low-damage bearing steel surface and application thereof 西南交通大学 2021-06-29 CN claimed
EP-3464446-B1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2021-06-23 EP claimed
CN-109476874-B Two-part cyanoacrylate curable adhesive systems 汉高知识产权控股有限责任公司 2021-04-16 CN claimed
CN-111116573-A Near-infrared fluorescent probe for simultaneously detecting DNA and RNA under dual channels and preparation method and application thereof 中山大学 2020-05-08 CN claimed
EP-3464446-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2019-04-10 EP claimed
US-10100235-B2 Two-part cyanoacrylate curable adhesive system Henkel IP & Holding GmbH (DE) 2018-10-16 US claimed
WO-2017202698-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2017-11-30 WO claimed
US-20170335151-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM HENKEL AG & CO. KGAA (DE) 2017-11-23 US claimed
US-20260125346-A1 Isoquinolinone Derivatives and 4H-Quinolizinone Derivatives and Pharmaceutical Compositions Thereof for the Treatment of Disease BEONE MEDICINES I GMBH (CH) 2026-05-07 US disclosed
EP-4721737-A1 USE OF PHARMACEUTICAL COMPOSITION COMPRISING COMPOUND HAVING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE FOR TREATING ANEMIA-RELATED DISEASES Scinnohub Pharmaceutical Co., Ltd. (CN) 2026-04-08 EP disclosed
EP-4709725-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF Progentos Therapeutics, Inc. (US) 2026-03-18 EP disclosed
EP-4685143-A1 DOUBLE REGULATOR FOR MGLUR5 AND HDAC6 AND USE THEREOF Vivozon,Inc. (KR) 2026-01-28 EP disclosed
US-20250346597-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEONE MEDICINES I GMBH (CH) 2025-11-13 US disclosed
US-20040180941-A1 3-(1-[3-(1,3-Benzothiazol-6-yl)propylcarbamoyl]cycloalkyl)propanoic acid derivatives as NEP inhibitors PFIZER INC 2004-09-16 US disclosed
US-20040132046-A1 Synthesis and evaluation of new cyanine dyes as minor groove of [POLY (dA-dT)]2 binders LIGHT UP TECHNOLOGIES AB (SE) 2004-07-08 US disclosed
US-20040116399-A1 Inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. 2004-06-17 US disclosed
US-20040116399-A1 Inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. 2004-06-17 US disclosed
EP-1390433-A1 SYNTHESIS AND EVALUATION OF NEW CYANINE DYES AS MINOR GROOVE OF POLY(DA-DT)] 2 BINDERS Light Up Technologies AB (SE) 2004-02-25 EP disclosed
WO-2002090443-A1 SYNTHESIS AND EVALUATION OF NEW CYANINE DYES AS MINOR GROOVE OF [POLY(DA-DT)]2 BINDERS LIGHT UP TECHNOLOGIES AB (SE) 2002-11-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040180941-A1 3-(1-[3-(1,3-Benzothiazol-6-yl)propylcarbamoyl]cycloalkyl)propanoic acid derivatives as NEP inhibitors MME, PREP, DNPEP SMN1; SMN2 3498/4885RAB9A 3193/4885NPC1 1004/4885
US-20250346597-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES DGKG, DGKA, DGKK SMN1; SMN2 4584/4885RAB9A 1548/4885NPC1 1908/4885
US-20260125346-A1 Isoquinolinone Derivatives and 4H-Quinolizinone Derivatives and Pharmaceutical Compositions Thereof for the Treatment of Disease NR3C1, NR3C2, PIK3R4 SMN1; SMN2 1452/4885RAB9A 260/4885NPC1 151/4885
US-20040132046-A1 Synthesis and evaluation of new cyanine dyes as minor groove of [POLY (dA-dT)]2 binders DRD4, FUT4, DRD1 SMN1; SMN2 4549/4885RAB9A 3345/4885NPC1 3194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.