Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxirane SCHEMBL8581231 | 0.91 | ALDH1A1 (0.67) | ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL28288392 | 0.90 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2 | |
| Dioxane SCHEMBL9508711 | 0.88 | ALDH1A1 (0.62) | ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2 | |
| Acetone SCHEMBL4989243 | 0.82 | — | — | |
| Acetic Acid SCHEMBL1704981 | 0.79 | — | — | |
| Fluoride SCHEMBL27342145 | 0.78 | — | — | |
| Tetrahydrofuran SCHEMBL4337006 | 0.78 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2 | |
| Tetrahydrofuran SCHEMBL1938419 | 0.78 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2 | |
| Ethyl Acetate SCHEMBL28471771 | 0.75 | ALDH1A1 (0.64) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL9866292 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1525309-B1 | STABILISATION OF NUCLEIC ACIDS | CYCLOPS GENOME SCIENCES LTD (GB) | 2012-04-18 | — | — | EP | disclosed |
| EP-1525309-A2 | STABILISATION OF NUCLEIC ACIDS | CYCLOPS GENOME SCIENCES LIMITED (GB) | 2005-04-27 | — | — | EP | disclosed |
| WO-2004013155-A2 | STABILISATION OF NUCLEIC ACIDS | CYCLOPS GENOME SCIENCES LIMITED (GB) | 2004-02-12 | — | — | WO | disclosed |