SCHEMBL23665563

SCHEMBL23665563

OC[C@H]1O[C@@H](O)C(O)C1OP(O)(O)=S

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ INPP5A Q14642 1/20 0.40
▸ SLC2A1 P11166 1/20 0.36
▸ FBP1 P09467 1/20 0.33
▸ ALDH1A1 P00352 2/20 0.31
▸ TSHR P16473 2/20 0.31
▸ LMNA P02545 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7798872 0.81 SMPD1 (0.50) INPP5A
SCHEMBL4191662 0.81 SMPD1 (0.50) INPP5A
SCHEMBL4442196 0.81 SMPD1 (0.50) INPP5A
SCHEMBL23665561 0.79 MAPK1 (0.33) SLC2A1FBP1
SCHEMBL30412792 0.76 ITPR3 (0.52) INPP5A
SCHEMBL8859419 0.76 ITPR3 (0.52) INPP5A
SCHEMBL6393369 0.75 FBP1 (0.37) SLC2A1FBP1
SCHEMBL23665560 0.73 FBP1 (0.35) SLC2A1FBP1
SCHEMBL30237668 0.72 SMPD1 (0.54) INPP5A
SCHEMBL16351395 0.72 L3MBTL1 (0.46) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210222165-A1 Chemically Ligated RNAs for CRISPR/Cas9-lgRNA Complexes as Antiviral Therapeutic Agents DR MINGHONG ZHONG (US) 2021-07-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210222165-A1 Chemically Ligated RNAs for CRISPR/Cas9-lgRNA Complexes as Antiviral Therapeutic Agents TRDMT1, SRRT, ZFR INPP5A 4314/4885SLC2A1 4416/4885FBP1 3231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback