Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9946439 | 0.81 | OPRM1 (0.45) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL18409994 | 0.80 | ITGB3 (0.40) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| SCHEMBL14898724 | 0.80 | RORC (0.38) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| SCHEMBL17057358 | 0.80 | NPC1 (0.47) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL10305031 | 0.77 | OPRM1 (0.50) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL14305080 | 0.77 | DPP4 (0.45) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL16215801 | 0.77 | DPP4 (0.41) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL1347525 | 0.77 | DPP4 (0.41) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL18082769 | 0.76 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL4830838 | 0.76 | DPP4 (0.46) | HPGDDPP4DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2670764-B1 | C-28 AMINES OF C-3 MODIFIED BETULINIC ACID DERIVATIVES AS HIV MATURATION INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-09-02 | — | — | EP | disclosed |