SCHEMBL17060528

SCHEMBL17060528

CCC(Cl)c1cc[c]cc1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
ATM Q13315 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5607146 0.82 TDP1 (0.42) TSHRMAPK1ATMTDP1L3MBTL1
SCHEMBL27294325 0.79 BDKRB2 (0.32) TSHR
SCHEMBL7399701 0.78
SCHEMBL13594208 0.75 LMNA (0.52) TSHRTDP1
SCHEMBL212179 0.75 LMNA (0.52) TSHRTDP1
SCHEMBL6578290 0.75 CYP17A1 (0.36) TSHRTDP1
SCHEMBL816075 0.75 ADRA2A (0.42) TDP1
SCHEMBL11684533 0.74 ESR1 (0.32)
SCHEMBL25334 0.73 ALDH1A1 (0.40) TSHRTDP1L3MBTL1
SCHEMBL18585352 0.73 LMNA (0.50) TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104893290-B Radiation-curable silicone composition 信越化学工业株式会社 2020-01-21 CN disclosed
US-9834678-B2 Radiation-curable silicone composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-12-05 US disclosed
EP-2915843-B1 RADIATION-CURABLE SILICONE COMPOSITION SHINETSU CHEMICAL CO (JP) 2017-11-22 EP disclosed
US-20150252193-A1 RADIATION-CURABLE SILICONE COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-09-10 US disclosed
EP-2915843-A1 Radiation-curable silicone composition Shin-Etsu Chemical Co., Ltd. (JP) 2015-09-09 EP disclosed
CN-104893290-A Radiation-curable silicone composition SHINETSU CHEMICAL CO 2015-09-09 CN disclosed