Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.44 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21939337 | 0.89 | CYP2D6 (0.76) | CYP2D6LMNAMAPK1SRCCES2 | |
| Ethylene SCHEMBL17060540 | 0.83 | CYP2D6 (0.67) | CYP2D6LMNAMAPK1SRCCES2 | |
| Mandelic Acid SCHEMBL8744861 | 0.79 | LMNA (0.78) | CYP2D6LMNAMAPK1SRCGABBR2 | |
| Mandelic Acid SCHEMBL1672106 | 0.79 | LMNA (0.78) | CYP2D6LMNAMAPK1SRCGABBR2 | |
| SCHEMBL7824857 | 0.78 | CYP2D6 (1.00) | CYP2D6LMNAMAPK1SRCCES2 | |
| SCHEMBL11315838 | 0.78 | CYP2D6 (1.00) | CYP2D6LMNAMAPK1SRCCES2 | |
| SCHEMBL7815004 | 0.78 | CYP2D6 (1.00) | CYP2D6LMNAMAPK1SRCCES2 | |
| SCHEMBL659768 | 0.78 | CYP2D6 (1.00) | CYP2D6LMNAMAPK1SRCCES2 | |
| Diphenylacetic Acid SCHEMBL29047740 | 0.77 | CTSD (0.52) | CYP2D6LMNAMAPK1SRCGABBR2 | |
| SCHEMBL3704070 | 0.77 | CYP2D6 (0.56) | CYP2D6LMNAMAPK1SRCCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3113803-B1 | HYGIENE ARTICLE COMPRISING AN EFFECTIVE ODOUR CONTROL SYSTEM | ONTEX BVBA (BE) | 2019-02-13 | — | — | EP | claimed |
| US-20170216481-A1 | HYGIENE ARTICLE COMPRISING AN EFFECTIVE ODOUR CONTROL SYSTEM | ONTEX BV (BE) | 2017-08-03 | — | — | US | claimed |
| EP-3113803-A1 | HYGIENE ARTICLE COMPRISING AN EFFECTIVE ODOUR CONTROL SYSTEM | Ontex BVBA (BE) | 2017-01-11 | — | — | EP | claimed |
| WO-2015132267-A1 | HYGIENE ARTICLE COMPRISING AN EFFECTIVE ODOUR CONTROL SYSTEM | ONTEX BVBA (BE) | 2015-09-11 | — | — | WO | claimed |
| EP-2915547-A1 | Hygiene article comprising an effective odour control system | Ontex BVBA (BE) | 2015-09-09 | — | — | EP | claimed |
| EP-3113803-B1 | HYGIENE ARTICLE COMPRISING AN EFFECTIVE ODOUR CONTROL SYSTEM | ONTEX BVBA (BE) | 2019-02-13 | — | — | EP | disclosed |
| US-20170216481-A1 | HYGIENE ARTICLE COMPRISING AN EFFECTIVE ODOUR CONTROL SYSTEM | ONTEX BV (BE) | 2017-08-03 | — | — | US | disclosed |
| EP-3113803-A1 | HYGIENE ARTICLE COMPRISING AN EFFECTIVE ODOUR CONTROL SYSTEM | Ontex BVBA (BE) | 2017-01-11 | — | — | EP | disclosed |
| WO-2015132267-A1 | HYGIENE ARTICLE COMPRISING AN EFFECTIVE ODOUR CONTROL SYSTEM | ONTEX BVBA (BE) | 2015-09-11 | — | — | WO | disclosed |
| EP-2915547-A1 | Hygiene article comprising an effective odour control system | Ontex BVBA (BE) | 2015-09-09 | — | — | EP | disclosed |