Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28639602 | 0.77 | CAMK2A (0.46) | CAMK2AGPR84FFAR1FFAR4KDM4E | |
| SCHEMBL17063554 | 0.74 | THRB (0.40) | CAMK2AGPR84FFAR1FFAR4 | |
| SCHEMBL2527134 | 0.73 | ALDH1A1 (0.42) | CAMK2AGPR84FFAR1FFAR4KDM4E | |
| SCHEMBL7723432 | 0.73 | CAMK2A (0.59) | CAMK2AGPR84FFAR1FFAR4KDM4E | |
| SCHEMBL1399301 | 0.71 | CAMK2A (0.40) | CAMK2AGPR84FFAR1FFAR4KDM4E | |
| SCHEMBL9390983 | 0.71 | CES2 (0.50) | — | |
| SCHEMBL7797219 | 0.71 | CES2 (0.50) | — | |
| SCHEMBL2993421 | 0.71 | CES2 (0.50) | — | |
| SCHEMBL932701 | 0.70 | KMT2A (0.55) | GPR84FFAR1FFAR4 | |
| SCHEMBL29505046 | 0.70 | CAMK2A (0.56) | CAMK2AGPR84FFAR1FFAR4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325014-B1 | GAMMA-HYDROXYBUTYRATE COMPOSITIONS CONTAINING CARBOHYDRATE CARRIERS | JPI COMMERCIAL LLC (US) | 2012-05-23 | — | — | EP | disclosed |
| US-7015200-B2 | Carbohydrates conjugated to optionally protected 4-hydroxybutyric acid; enhance the uptake of the drug and allows effective drug delivery to treat GHB-treatable disorders such as sleep disorders or drug withdrawal | ORPHAN MEDICAL, INC. (US) | 2006-03-21 | — | — | US | disclosed |
| US-20040092455-A1 | Carbohydrates conjugated to optionally protected 4-hydroxybutyric acid; enhance the uptake of the drug and allows effective drug delivery to treat GHB-treatable disorders such as sleep disorders or drug withdrawal | U.S. BANK NATIONAL ASSOCIATION | 2004-05-13 | — | — | US | disclosed |
| EP-1325014-A2 | GAMMA-HYDROXYBUTYRATE COMPOSITIONS CONTAINING CARBOHYDRATE, LIPID OR AMINO ACID CARRIERS | Orphan Medical Inc. (US) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002024715-A2 | GAMMA-HYDROXYBUTYRATE COMPOSITIONS CONTAINING CARBOHYDRATE, LIPID OR AMINO ACID CARRIERS | ORPHAN MEDICAL, INC. (US) | 2002-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092455-A1 | Carbohydrates conjugated to optionally protected 4-hydroxybutyric acid; enhance the uptake of the drug and allows effective drug delivery to treat GHB-treatable disorders such as sleep disorders or drug withdrawal | SLC2A4, SLC2A1, SLC2A3 | CAMK2A 1471/4885GPR84 439/4885FFAR1 177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.