Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 5/20 | 0.46 |
| ▸ | CTSB | P07858 | 4/20 | 0.46 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | EP300 | Q09472 | 2/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15337732 | 0.83 | BACE1 (0.42) | EP300KAT2BKAT8BACE1GCGR | |
| SCHEMBL3459911 | 0.73 | IDO1 (0.50) | CTSLCAPN1CTSBIDO1EP300 | |
| SCHEMBL3459912 | 0.73 | IDO1 (0.50) | CTSLCAPN1CTSBIDO1EP300 | |
| SCHEMBL19872825 | 0.71 | GLA (0.42) | HDAC3LMNAMAPT | |
| SCHEMBL17066486 | 0.69 | TYR (0.44) | CAPN1BACE1LMNAMAPT | |
| SCHEMBL501996 | 0.69 | IDO1 (0.59) | CTSLCAPN1CTSBIDO1EP300 | |
| SCHEMBL16048249 | 0.68 | CTSL (0.64) | CTSLCAPN1CTSBIDO1BACE1 | |
| SCHEMBL16048251 | 0.68 | CTSL (0.64) | CTSLCAPN1CTSBIDO1BACE1 | |
| SCHEMBL20879395 | 0.68 | — | — | |
| SCHEMBL17066487 | 0.67 | TYR (0.61) | EP300BACE1HDAC3KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9125973-B2 | Antimicrobial housing and cover for a medical device | BAXTER INTERNATIONAL INC. (US) | 2015-09-08 | — | — | US | disclosed |