Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15712970 | 0.94 | PTGS1 (0.37) | PTGS1PTGS2ALDH1A1HPGDMEN1 | |
| SCHEMBL17060109 | 0.86 | NPC1 (0.31) | ALDH1A1NPC1RAB9A | |
| SCHEMBL2235899 | 0.85 | PTGS1 (0.42) | PTGS1PTGS2ALDH1A1HPGDMEN1 | |
| SCHEMBL22499703 | 0.84 | PTGS1 (0.39) | PTGS1PTGS2ALDH1A1HPGDMEN1 | |
| SCHEMBL18632069 | 0.84 | PTGS1 (0.39) | PTGS1PTGS2ALDH1A1HPGDMEN1 | |
| Hydrochloric Acid SCHEMBL28677533 | 0.83 | PTGS1 (0.38) | PTGS1PTGS2ALDH1A1HPGDMEN1 | |
| SCHEMBL2234262 | 0.83 | PTGS1 (0.40) | PTGS1PTGS2ALDH1A1HPGDMEN1 | |
| SCHEMBL22499740 | 0.82 | PTGS1 (0.37) | PTGS1PTGS2ALDH1A1HPGDMEN1 | |
| Hydrochloric Acid SCHEMBL30557801 | 0.82 | PTGS1 (0.37) | PTGS1PTGS2ALDH1A1HPGDMEN1 | |
| SCHEMBL28677531 | 0.81 | PTGS1 (0.36) | PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3121187-B1 | METALLOCENE COMPLEX AND METHOD FOR MANUFACTURING OLEFIN POLYMER | JAPAN POLYPROPYLENE CORP (JP) | 2018-10-10 | — | — | EP | disclosed |
| US-9963522-B2 | Metallocene complex and method for producing olefin polymer | JAPAN POLYPROPYLENE CORPORATION (JP) | 2018-05-08 | — | — | US | disclosed |
| US-9902749-B2 | Metallocene complex and olefin polymerization method | JAPAN POLYPROPYLENE CORPORATION (JP) | 2018-02-27 | — | — | US | disclosed |
| US-9902749-B2 | Metallocene complex and olefin polymerization method | JAPAN POLYPROPYLENE CORPORATION (JP) | 2018-02-27 | — | — | US | disclosed |
| US-9902749-B2 | Metallocene complex and olefin polymerization method | JAPAN POLYPROPYLENE CORPORATION (JP) | 2018-02-27 | — | — | US | disclosed |
| CN-104781270-B | Metallocene complexes and olefin polymerization process | 日本聚丙烯株式会社 | 2017-10-24 | — | — | CN | disclosed |
| US-20170081431-A1 | METALLOCENE COMPLEX AND METHOD FOR PRODUCING OLEFIN POLYMER | JAPAN POLYPROPYLENE CORPORATION (JP) | 2017-03-23 | — | — | US | disclosed |
| EP-3121187-A1 | METALLOCENE COMPLEX AND METHOD FOR MANUFACTURING OLEFIN POLYMER | Japan Polypropylene Corporation (JP) | 2017-01-25 | — | — | EP | disclosed |
| US-20150266914-A1 | METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD | JAPAN POLYPROPYLENE CORPORATION (JP) | 2015-09-24 | — | — | US | disclosed |
| US-20150266914-A1 | METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD | JAPAN POLYPROPYLENE CORPORATION (JP) | 2015-09-24 | — | — | US | disclosed |
| US-20150266914-A1 | METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD | JAPAN POLYPROPYLENE CORPORATION (JP) | 2015-09-24 | — | — | US | disclosed |
| EP-2915816-A1 | METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD | Japan Polypropylene Corporation (JP) | 2015-09-09 | — | — | EP | disclosed |
| CN-104781270-A | Metallocene complexes and olefin polymerization process | JAPAN POLYPROPYLENE CORP | 2015-07-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170081431-A1 | METALLOCENE COMPLEX AND METHOD FOR PRODUCING OLEFIN POLYMER | PPOX, ALOX12, PORCN | PTGS1 266/4885PTGS2 176/4885ALDH1A1 1301/4885 |
| US-20150266914-A1 | METALLOCENE COMPLEX AND OLEFIN POLYMERIZATION METHOD | POR, OPRM1, ALOX12 | PTGS1 201/4885PTGS2 182/4885ALDH1A1 986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.