Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1706845 | 0.95 | ATM (0.40) | SLC6A3ATMCCNT1HTR2ACACNA1G | |
| SCHEMBL1706846 | 0.95 | ATM (0.40) | SLC6A3ATMCCNT1HTR2ACACNA1G | |
| SCHEMBL1706817 | 0.91 | SLC6A3 (0.43) | SLC6A3MAPK1CCR3ATMCCNT1 | |
| SCHEMBL1706819 | 0.91 | SLC6A3 (0.43) | SLC6A3MAPK1CCR3ATMCCNT1 | |
| SCHEMBL1707102 | 0.89 | SLC6A3 (0.41) | SLC6A3MAPK1CCR3ATMHTR2A | |
| SCHEMBL1707095 | 0.89 | SLC6A3 (0.41) | SLC6A3MAPK1CCR3ATMHTR2A | |
| SCHEMBL1707646 | 0.89 | ROCK2 (0.40) | MAPK1CCR3ALDH1A1KDM4EKAT2B | |
| Hydrochloric Acid SCHEMBL1706803 | 0.89 | SLC6A3 (0.41) | SLC6A3MAPK1CCR3ATMHTR2A | |
| Hydrochloric Acid SCHEMBL1707440 | 0.89 | SLC6A3 (0.41) | SLC6A3MAPK1CCR3ATMHTR2A | |
| Hydrochloric Acid SCHEMBL1706805 | 0.89 | SLC6A3 (0.41) | SLC6A3MAPK1CCR3ATMHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981877-B1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2012-04-18 | — | — | EP | disclosed |