SCHEMBL170687

SCHEMBL170687

Cc1ccc(-c2ccc(N(c3ccc(C)cc3)c3ccc(OC=O)cc3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.35
TSHR P16473 3/20 0.34
ALDH1A1 P00352 1/20 0.34
ACHE P22303 1/20 0.34
CYP3A4 P08684 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
LMNA P02545 1/20 0.33
CYP2A6 P11509 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
RELA Q04206 1/20 0.32
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32
KDM4E B2RXH2 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20274359 1.00 ALOX5 (0.35) ALOX5TSHRALDH1A1ACHECYP3A4
SCHEMBL15500191 0.94 TSHR (0.38) TSHRALDH1A1ACHECYP3A4MEN1
SCHEMBL14585887 0.94 PPARG (0.38) ALOX5ALDH1A1MEN1KMT2ALMNA
SCHEMBL14585891 0.94 APP (0.39) ALDH1A1CYP3A4MEN1KMT2ALMNA
SCHEMBL14585892 0.89 HTT (0.45) ALOX5MEN1KMT2ALMNAHTT
SCHEMBL4570686 0.89 ACHE (0.42) ALOX5TSHRACHECYP3A4MEN1
SCHEMBL14585885 0.87 HTT (0.44) TSHRALDH1A1CYP3A4MEN1KMT2A
SCHEMBL22448222 0.86 THRB (0.43) TSHRALDH1A1KMT2ALMNAMAPT
SCHEMBL14585883 0.84 ALKBH3 (0.42) MAPT
SCHEMBL14585893 0.84 HSD17B1 (0.40) ALDH1A1ACHECYP3A4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2017676-B1 Image forming apparatus, image forming method, and process cartridge RICOH CO LTD (JP) 2014-07-23 EP disclosed
EP-1847881-B1 Image forming apparatus, image forming method, and process cartridge RICOH CO LTD (JP) 2012-03-07 EP disclosed
EP-1847881-A2 Image forming apparatus, image forming method, and process cartridge Ricoh Company, Ltd. (JP) 2007-10-24 EP disclosed