SCHEMBL4570686

SCHEMBL4570686

Cc1ccc(-c2ccc(OC=O)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.42
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
CYP2A6 P11509 1/20 0.41
LMNA P02545 1/20 0.40
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
RELA Q04206 1/20 0.39
ALOX5 P09917 3/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
KDM4E B2RXH2 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TEAD4 Q15561 1/20 0.37
PPARG P37231 1/20 0.37
PPARA Q07869 1/20 0.37
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL95902 0.93 ACHE (0.48) ACHECYP3A4TSHRCYP2A6LMNA
SCHEMBL28837871 0.91 ACHE (0.46) ACHECYP3A4TSHRCYP2A6LMNA
SCHEMBL20274359 0.89 ALOX5 (0.35) ACHECYP3A4TSHRCYP2A6LMNA
SCHEMBL170687 0.89 ALOX5 (0.35) ACHECYP3A4TSHRCYP2A6LMNA
SCHEMBL17297207 0.88 DRD1 (0.40) CYP2A6CA1CA2CA9NPC1
SCHEMBL15417644 0.87 TSHR (0.38) ACHECYP3A4TSHRCYP2A6LMNA
SCHEMBL18805146 0.86 TEAD4 (0.52) ACHECYP3A4TSHRCYP2A6LMNA
SCHEMBL14585891 0.83 APP (0.39) CYP3A4LMNAKMT2AMEN1CA9
SCHEMBL14585887 0.83 PPARG (0.38) LMNAKMT2AMEN1CA1CA2
SCHEMBL14284922 0.82 ALDH1A1 (0.52) ACHECYP2A6KMT2AMEN1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11649332-B2 Method of processing liquid crystal polymer film AZOTEK CO., LTD. (TW) 2023-05-16 US disclosed
EP-3048159-B1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2019-08-07 EP disclosed
EP-3029127-B1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2017-12-20 EP disclosed
EP-2837671-B1 Liquid crystalline medium MERCK PATENT GMBH (DE) 2017-10-25 EP disclosed
EP-2922933-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2017-02-01 EP disclosed
US-8940392-B2 Titanium based inorganic-organic hybrid solid material, method for preparing same and uses thereof UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) 2015-01-27 US disclosed
US-20120121904-A1 TITANIUM BASED INORGANIC-ORGANIC HYBRID SOLID MATERIAL, METHOD FOR PREPARING SAME AND USES THEREOF L'UNIVERSITE PIERRE ET MARIE CURIE, (PARIS 6) (FR) 2012-05-17 US disclosed