Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.53 |
| ▸ | NPC1 | O15118 | 12/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.53 |
| ▸ | CASP3 | P42574 | 3/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.53 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.50 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2228307 | 0.82 | ENPP3 (0.39) | RAB9ANPC1SMN1; SMN2CASP3SENP8 | |
| SCHEMBL17544821 | 0.81 | PDE4B (0.53) | RAB9ANPC1SMN1; SMN2CASP3SENP8 | |
| SCHEMBL21083458 | 0.81 | HDAC1 (0.54) | RAB9ANPC1SMN1; SMN2ENPP3ENPP1 | |
| SCHEMBL5539380 | 0.81 | NPC1 (0.50) | RAB9ANPC1SMN1; SMN2CASP3SENP8 | |
| SCHEMBL23176775 | 0.78 | TGFBR1 (0.38) | ENPP3ENPP1TSHRALDH1A1KDM4E | |
| SCHEMBL31607735 | 0.77 | KDM4E (0.56) | RAB9ANPC1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL6487009 | 0.77 | NPC1 (0.46) | RAB9ANPC1SMN1; SMN2CASP3SENP8 | |
| SCHEMBL7744187 | 0.75 | HDAC1 (0.49) | RAB9ANPC1SMN1; SMN2CASP3SENP8 | |
| SCHEMBL3951956 | 0.75 | ENPP3 (0.53) | RAB9ANPC1SMN1; SMN2CASP3SENP8 | |
| SCHEMBL31415531 | 0.74 | ALDH1A1 (0.47) | RAB9ANPC1SMN1; SMN2CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210095196-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2021-04-01 | — | — | US | disclosed |
| US-9493446-B2 | Orexin receptor antagonists which are [ortho bi-(hetero-)aryl]-[2-(meta bi-(hetero-)aryl)-pyrrolidin-1-yl]-methanone derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2016-11-15 | — | — | US | disclosed |
| US-20150252032-A1 | OREXIN RECEPTOR ANTAGONISTS WHICH ARE [ORTHO BI-(HETERO-)ARYL]-[2-(META BI-(HETERO-)ARYL)-PYRROLIDIN-1-YL]-METHANONE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2015-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210095196-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | SSB, RO60, OSBP | RAB9A 428/4885NPC1 2361/4885SMN1; SMN2 4645/4885 |
| US-20150252032-A1 | OREXIN RECEPTOR ANTAGONISTS WHICH ARE [ORTHO BI-(HETERO-)ARYL]-[2-(META BI-(HETERO-)ARYL)-PYRROLIDIN-1-YL]-METHANONE DERIVATIVES | HCRTR2, HCRTR1, OXTR | RAB9A 2830/4885NPC1 1248/4885SMN1; SMN2 2096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.