SCHEMBL17070930

SCHEMBL17070930

CN1C(=O)C(c2ccccc2)C(=O)c2ccccc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.57
KDM4E B2RXH2 1/20 0.57
ALDH1A1 P00352 1/20 0.57
TP53 P04637 2/20 0.55
MAPT P10636 2/20 0.55
LMNA P02545 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP3A4 P08684 1/20 0.55
MAPK1 P28482 1/20 0.55
HTR2B P41595 1/20 0.55
GABRP O00591 1/20 0.50
GABRD O14764 1/20 0.50
GABRA1 P14867 1/20 0.50
GABRB1 P18505 1/20 0.50
GABRG2 P18507 1/20 0.50
GABRB3 P28472 1/20 0.50
GABRA5 P31644 1/20 0.50
GABRA3 P34903 1/20 0.50
GABRA2 P47869 1/20 0.50
GABRB2 P47870 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28366523 0.84 CCKBR (0.49) HPGDKDM4EALDH1A1GABRPGABRD
SCHEMBL9952138 0.79 CHEK1 (0.49) HPGDKDM4EALDH1A1TP53MAPT
SCHEMBL29915854 0.79 CHEK1 (0.49) HPGDKDM4EALDH1A1TP53MAPT
SCHEMBL14372140 0.77 KDM4E (0.62) HPGDKDM4EALDH1A1MAPTLMNA
SCHEMBL28335676 0.75 KDM4E (0.60) HPGDKDM4EALDH1A1MAPTLMNA
SCHEMBL17811461 0.74 LMNA (0.44) HPGDALDH1A1TP53MAPTLMNA
SCHEMBL64294 0.74 KMT2A (0.48) KDM4EALDH1A1TP53MAPTLMNA
Phenindione SCHEMBL33831 0.72 MAPT (1.00) HPGDKDM4ETP53MAPTLMNA
Phenindione SCHEMBL29388073 0.72 MAPT (1.00) HPGDKDM4ETP53MAPTLMNA
SCHEMBL13391522 0.72 KDM4E (0.57) HPGDKDM4EALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10254456-B2 Polarizing plate composition, polarizing plate protective film, polarizer, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2019-04-09 US disclosed
US-20160370523-A1 POLARIZING PLATE COMPOSITION, POLARIZING PLATE PROTECTIVE FILM, POLARIZER, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-22 US disclosed
US-20160370523-A1 POLARIZING PLATE COMPOSITION, POLARIZING PLATE PROTECTIVE FILM, POLARIZER, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-22 US disclosed
US-9507067-B2 Polarizing plate and liquid crystal display device including the same FUJIFILM CORPORATION (JP) 2016-11-29 US disclosed
US-9507067-B2 Polarizing plate and liquid crystal display device including the same FUJIFILM CORPORATION (JP) 2016-11-29 US disclosed
US-20160341860-A1 POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE INCLUDING SAME, AND METHOD FOR PRODUCING POLARIZING PLATE FUJIFILM CORPORATION (JP) 2016-11-24 US disclosed
US-20160341860-A1 POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE INCLUDING SAME, AND METHOD FOR PRODUCING POLARIZING PLATE FUJIFILM CORPORATION (JP) 2016-11-24 US disclosed
US-20150253479-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE INCLUDING THE SAME FUJIFILM CORPORATION (JP) 2015-09-10 US disclosed
US-20150253479-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE INCLUDING THE SAME FUJIFILM CORPORATION (JP) 2015-09-10 US disclosed