Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | HPGD | P15428 | 7/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.69 |
| ▸ | CASP1 | P29466 | 6/20 | 0.69 |
| ▸ | CASP7 | P55210 | 6/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.69 |
| ▸ | GAA | P10253 | 5/20 | 0.69 |
| ▸ | GLA | P06280 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | STAT6 | P42226 | 1/20 | 0.69 |
| ▸ | ERAP1 | Q9NZ08 | 5/20 | 0.67 |
| ▸ | CA9 | Q16790 | 7/20 | 0.60 |
| ▸ | CA12 | O43570 | 5/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.60 |
| ▸ | ACHE | P22303 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Esculetin SCHEMBL165749 | 1.00 | ALDH1A1 (0.69) | ALDH1A1HPGDKDM4ECASP1CASP7 | |
| Esculin SCHEMBL8155952 | 0.85 | ALDH1A1 (0.96) | ALDH1A1HPGDKDM4ECASP1CASP7 | |
| SCHEMBL11111897 | 0.84 | ALDH1A1 (0.65) | ALDH1A1HPGDKDM4ECASP1CASP7 | |
| SCHEMBL13784420 | 0.83 | ALDH1A1 (0.93) | ALDH1A1HPGDKDM4ECASP1CASP7 | |
| SCHEMBL1536006 | 0.83 | ALDH1A1 (0.93) | ALDH1A1HPGDKDM4ECASP1CASP7 | |
| SCHEMBL7762578 | 0.83 | ALDH1A1 (0.93) | ALDH1A1HPGDKDM4ECASP1CASP7 | |
| SCHEMBL29398048 | 0.83 | ALDH1A1 (0.93) | ALDH1A1HPGDKDM4ECASP1CASP7 | |
| Esculin SCHEMBL13096298 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ECASP1CASP7 | |
| Esculin SCHEMBL2893 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ECASP1CASP7 | |
| Esculin SCHEMBL8035285 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ECASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828407-B2 | Water soluble and activable phenolic derivatives with dermocosmetic and therapeutic applications and process for preparing said derivatives | LIBRAGEN (FR) | 2017-11-28 | — | — | US | disclosed |
| US-20140088030-A1 | WATER SOLUBLE AND ACTIVABLE PHENOLICS DERIVATIVES WITH DERMOCOSMETIC AND THERAPEUTIC APPLICATIONS AND PROCESS FOR PREPARING SAID DERIVATIVES | LIBRAGEN (FR) | 2014-03-27 | — | — | US | disclosed |
| EP-2027279-B1 | Phenolic compounds with cosmetic and therapeutic applications | LIBRAGEN (FR) | 2012-04-18 | — | — | EP | disclosed |
| US-20090233876-A1 | Water Soluble and Activable Phenolics Derivatives with Dermocosmetic and Therapeutic Applications and Process for Preparing Said Derivatives | LIBRAGEN (FR) | 2009-09-17 | — | — | US | disclosed |
| EP-1867729-A1 | Water soluble phenolics derivatives with dermocosmetic and therapeutic applications | Libragen (FR) | 2007-12-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233876-A1 | Water Soluble and Activable Phenolics Derivatives with Dermocosmetic and Therapeutic Applications and Process for Preparing Said Derivatives | UGGT1, TYR, LCT | ALDH1A1 1189/4885HPGD 452/4885KDM4E 1025/4885 |
| US-20140088030-A1 | WATER SOLUBLE AND ACTIVABLE PHENOLICS DERIVATIVES WITH DERMOCOSMETIC AND THERAPEUTIC APPLICATIONS AND PROCESS FOR PREPARING SAID DERIVATIVES | UGGT1, TYR, G6PD | ALDH1A1 1534/4885HPGD 397/4885KDM4E 949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.