Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.30 |
| ▸ | XIAP | P98170 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707982 | 0.85 | FFAR1 (0.33) | LTB4RLTB4R2HTR2A | |
| SCHEMBL3716544 | 0.82 | HTR2A (0.33) | HTR2ABACE1BACE2 | |
| SCHEMBL10011831 | 0.80 | FFAR1 (0.48) | — | |
| SCHEMBL10011110 | 0.80 | FFAR1 (0.48) | — | |
| SCHEMBL10009234 | 0.80 | FFAR1 (0.48) | — | |
| SCHEMBL1707916 | 0.77 | MTOR (0.36) | — | |
| SCHEMBL1707821 | 0.76 | KDM4C (0.37) | LTB4RLTB4R2ACHE | |
| SCHEMBL3715877 | 0.74 | HTR2A (0.32) | HTR2A | |
| SCHEMBL1708581 | 0.73 | POLB (0.31) | — | |
| SCHEMBL1707702 | 0.72 | LTB4R (0.30) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |