Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708581 | 0.76 | POLB (0.31) | KDM4ELMNATP53MAPTHTT | |
| SCHEMBL1707705 | 0.74 | LTB4R (0.33) | HTR2A | |
| SCHEMBL3716544 | 0.74 | HTR2A (0.33) | HTR2AHTR1AHTR7HTR2BTMEM97 | |
| SCHEMBL10009234 | 0.73 | FFAR1 (0.48) | — | |
| SCHEMBL10011831 | 0.73 | FFAR1 (0.48) | — | |
| SCHEMBL10011110 | 0.73 | FFAR1 (0.48) | — | |
| SCHEMBL31136608 | 0.71 | HTR1A (0.41) | HTR2AHTR1AHTR7HTR2BTMEM97 | |
| SCHEMBL26975051 | 0.66 | HTR2B (0.44) | HTR2AHTR1AHTR7HTR2BTMEM97 | |
| SCHEMBL10011137 | 0.64 | P2RX7 (0.37) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL5784635 | 0.61 | MEN1 (0.42) | HTR2AHTR2BLMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |