Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3798510 | 0.87 | ALDH1A1 (0.33) | RORCALDH1A1MAPTMAPK1 | |
| SCHEMBL1708681 | 0.80 | FFAR1 (0.40) | — | |
| SCHEMBL3798508 | 0.80 | FFAR1 (0.46) | — | |
| SCHEMBL1708101 | 0.80 | RORC (0.33) | RORC | |
| SCHEMBL1708581 | 0.77 | POLB (0.31) | MAPT | |
| SCHEMBL1708277 | 0.74 | RORC (0.33) | RORC | |
| SCHEMBL1708593 | 0.73 | TSHR (0.36) | ALDH1A1MAPTMAPK1 | |
| SCHEMBL1707934 | 0.73 | NPC1 (0.37) | ALDH1A1MAPT | |
| SCHEMBL1708342 | 0.72 | NPC1 (0.35) | ALDH1A1MAPTMAPK1 | |
| SCHEMBL1708004 | 0.70 | KCNK3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |