Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3861376 | 0.76 | HPGD (0.76) | HPGDPOLBALDH1A1MEN1MAPK1 | |
| SCHEMBL17080657 | 0.75 | POLB (0.43) | HPGDPOLBALDH1A1KDM4EHTT | |
| SCHEMBL17080658 | 0.74 | LMNA (0.55) | HPGDPOLBALDH1A1HTTMEN1 | |
| SCHEMBL6988348 | 0.74 | ALDH1A1 (0.48) | HPGDPOLBALDH1A1KDM4EMEN1 | |
| SCHEMBL13857741 | 0.73 | TSHR (0.53) | HPGDPOLBALDH1A1KDM4EMEN1 | |
| SCHEMBL26757982 | 0.72 | KMT2A (0.51) | HPGDPOLBALDH1A1KDM4EMEN1 | |
| SCHEMBL20978806 | 0.72 | HPGD (0.41) | HPGDPOLBALDH1A1MEN1MAPK1 | |
| SCHEMBL11767831 | 0.71 | ABCG2 (0.48) | HPGDPOLBALDH1A1HTTMEN1 | |
| SCHEMBL13162930 | 0.71 | NPC1 (0.60) | HPGDALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL2216523 | 0.71 | HPGD (0.54) | HPGDPOLBALDH1A1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9446149-B2 | Nanoparticles stabilized with nitrophenylboronic acid compositions | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-09-20 | — | — | US | disclosed |