SCHEMBL17082247

SCHEMBL17082247

CC1=Cc2c(-c3cccc4ccccc34)cccc2C1S(c1ccccc1)(c1ccccc1)C1C(C)=Cc2c1cccc2N1CCCc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
CRHBP P24387 1/20 0.32
MAPK1 P28482 1/20 0.32
CRHR2 Q13324 1/20 0.32
TUBB4A P04350 3/20 0.32
TUBB P07437 3/20 0.32
TUBA3C P0DPH7 3/20 0.32
TUBA1B P68363 3/20 0.32
TUBA4A P68366 3/20 0.32
TUBB4B P68371 3/20 0.32
TUBB3 Q13509 3/20 0.32
TUBB2A Q13885 3/20 0.32
TUBB8 Q3ZCM7 3/20 0.32
TUBA3E Q6PEY2 3/20 0.32
TUBA1A Q71U36 3/20 0.32
TUBA1C Q9BQE3 3/20 0.32
TUBB6 Q9BUF5 3/20 0.32
TUBB2B Q9BVA1 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17029431 0.89 MEN1 (0.40) MEN1KMT2AATMCRHBPMAPK1
SCHEMBL17082307 0.84 HTR7 (0.34) ROCK1HTR1AHTR7
SCHEMBL19336701 0.83 L3MBTL1 (0.33) CRHBPMAPK1CRHR2TUBB4ATUBB
SCHEMBL17952984 0.83 CHRM2 (0.34) MEN1KMT2AMAPK1TUBB4ATUBB
SCHEMBL17082287 0.83 HTR1A (0.31) HTR1AHTR7
SCHEMBL17082245 0.83 DRD2 (0.32) MEN1KMT2AATMHTR1AHTR7
SCHEMBL17074035 0.82 L3MBTL1 (0.35) MEN1KMT2ACRHBPMAPK1CRHR2
SCHEMBL17082257 0.81 MEN1 (0.34) MEN1KMT2AATMROCK1AKR1C3
SCHEMBL17082260 0.81
Hydrochloric Acid SCHEMBL19453221 0.79 ROCK1 (0.34) CRHBPMAPK1CRHR2TUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2918591-A1 NOVEL LIGAND COMPOUND, PREPARATION METHOD THEREFOR, TRANSITION METAL COMPOUND, AND PREPARATION METHOD THEREFOR LG Chem, Ltd. (KR) 2015-09-16 EP disclosed