Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | HTR5A | P47898 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18071526 | 0.91 | HTR2C (0.32) | HTR2CDRD2DRD4DRD3HTR5A | |
| SCHEMBL18071562 | 0.86 | DRD2 (0.34) | HTR2CDRD2DRD4DRD3HTR5A | |
| SCHEMBL15746360 | 0.86 | CASP3 (0.40) | DRD2DRD4DRD3HTR5A | |
| SCHEMBL15692902 | 0.77 | HPGDS (0.33) | DRD2DRD4DRD3HTR5A | |
| SCHEMBL15692818 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL15692943 | 0.76 | ALDH1A1 (0.32) | — | |
| SCHEMBL15692822 | 0.75 | HSD11B1 (0.37) | DRD2DRD4DRD3HTR5A | |
| SCHEMBL15692814 | 0.74 | DRD2 (0.35) | DRD2DRD4DRD3HTR5A | |
| SCHEMBL15692789 | 0.73 | DRD2 (0.34) | DRD2DRD4DRD3HTR5A | |
| SCHEMBL15773416 | 0.70 | DRD2 (0.33) | DRD2DRD4DRD3HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2730572-B1 | SPIRO COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS | SUNSHINE LAKE PHARMA CO LTD (CN) | 2015-09-16 | — | — | EP | disclosed |