Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 6/20 | 0.35 |
| ▸ | RAB9A | P51151 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708284 | 0.92 | MAPT (0.36) | SMN1; SMN2NPC1RAB9AMAPTKMT2A | |
| SCHEMBL1708680 | 0.91 | MTNR1A (0.39) | SMN1; SMN2NPC1RAB9AMAPTKMT2A | |
| SCHEMBL1708268 | 0.90 | SMN1; SMN2 (0.35) | SMN1; SMN2NPC1RAB9AMAPTKMT2A | |
| SCHEMBL1708070 | 0.87 | LMNA (0.40) | SMN1; SMN2NPC1RAB9AMAPTKMT2A | |
| SCHEMBL1708693 | 0.87 | SMN1; SMN2 (0.36) | SMN1; SMN2GFERNPC1RAB9AMAPT | |
| SCHEMBL1708140 | 0.87 | FFAR1 (0.38) | SMN1; SMN2GFERPIK3CDPIK3CAPIK3CB | |
| SCHEMBL1708302 | 0.87 | FFAR1 (0.43) | — | |
| SCHEMBL1708180 | 0.86 | SMN1; SMN2 (0.40) | SMN1; SMN2NPC1RAB9AMAPTKMT2A | |
| SCHEMBL1707875 | 0.86 | HPGD (0.37) | SMN1; SMN2GFERNPC1RAB9AMAPT | |
| SCHEMBL1708139 | 0.85 | GFER (0.39) | SMN1; SMN2GFERPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |