Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29871774 | 0.89 | LMNA (0.50) | CYP2A6CYP1A2LMNATP53PTPN1 | |
| SCHEMBL4194127 | 0.89 | LMNA (0.50) | CYP2A6CYP1A2LMNATP53PTPN1 | |
| SCHEMBL21675665 | 0.85 | PTPN1 (0.49) | CYP2A6CYP1A2LMNATP53PTPN1 | |
| SCHEMBL7843853 | 0.84 | AKR1B1 (0.41) | CYP2A6CYP1A2LMNATP53PTPN1 | |
| SCHEMBL18716081 | 0.82 | LMNA (0.49) | CYP2A6CYP1A2LMNATP53PTPN1 | |
| SCHEMBL8188647 | 0.82 | AKR1B1 (0.39) | CYP2A6CYP1A2LMNATP53PTPN1 | |
| SCHEMBL14201539 | 0.82 | CYP2A6 (0.52) | CYP2A6CYP1A2TDP1MAOBAGXT | |
| SCHEMBL14016921 | 0.81 | CYP1A2 (0.59) | CYP2A6CYP1A2LMNATP53PTPN1 | |
| SCHEMBL241798 | 0.81 | CYP1A2 (0.59) | CYP2A6CYP1A2LMNATP53PTPN1 | |
| SCHEMBL18636418 | 0.79 | CYP1A2 (0.52) | CYP2A6CYP1A2LMNATP53PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815823-B2 | Carbazole ketoxime ester high-photosensitivity photoinitiator | CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) | 2017-11-14 | — | — | US | disclosed |
| US-9656978-B2 | Acylpiperazines as inhibitors of transglutaminase and their use in medicine | ASTON UNIVERSITY (GB) | 2017-05-23 | — | — | US | disclosed |
| US-20150259310-A1 | Acylpiperazines as Inhibitors of Transglutaminase and Their Use in Medicine | ASTON UNIVERSITY (GB) | 2015-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150259310-A1 | Acylpiperazines as Inhibitors of Transglutaminase and Their Use in Medicine | ENPEP, ENPP2, MMP17 | CYP2A6 998/4885CYP1A2 283/4885TDP1 997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.