Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 3/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3715118 | 0.91 | PTGES (0.39) | NTRK1HCRTR1HCRTR2MAPT | |
| SCHEMBL1708584 | 0.89 | CD274 (0.41) | NTRK1HCRTR1HCRTR2EEDSUZ12 | |
| SCHEMBL1708466 | 0.86 | FFAR1 (0.49) | FFAR1 | |
| SCHEMBL10292316 | 0.85 | FFAR1 (0.40) | FFAR1NTRK1KLKB1CSF1RPIK3CA | |
| SCHEMBL1708225 | 0.85 | KLKB1 (0.35) | FFAR1NTRK1KLKB1TNIKPIK3CA | |
| SCHEMBL3719582 | 0.85 | WNT3A (0.39) | FFAR1ALDH1A1GAAMAPTEED | |
| SCHEMBL1708611 | 0.83 | POLB (0.33) | FFAR1POLBINSRIGF1RALDH1A1 | |
| SCHEMBL1708457 | 0.80 | STAT6 (0.37) | FFAR1ALDH1A1GAAMAPTEED | |
| SCHEMBL1707869 | 0.79 | STAT6 (0.36) | FFAR1ALDH1A1GAAMAPTEED | |
| SCHEMBL1708596 | 0.79 | INSR (0.35) | FFAR1POLBINSRIGF1RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |