Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanazole SCHEMBL6030091 | 0.76 | ALDH1A1 (0.36) | ALDH1A1TSHRKDM4EMEN1CYP1A2 | |
| Sulfuric Acid SCHEMBL129071 | 0.66 | CA5A (0.43) | ALDH1A1TSHRKDM4EMEN1CYP1A2 | |
| Sulfuric Acid SCHEMBL3344978 | 0.66 | CA5A (0.43) | ALDH1A1TSHRKDM4EMEN1CYP1A2 | |
| Sulfuric Acid SCHEMBL3338642 | 0.66 | CA5A (0.43) | ALDH1A1TSHRKDM4EMEN1CYP1A2 | |
| Sulfuric Acid SCHEMBL11529048 | 0.63 | CA5A (0.40) | ALDH1A1TSHRKDM4EMEN1CYP1A2 | |
| Sulfuric Acid SCHEMBL11564899 | 0.63 | CA5A (0.40) | ALDH1A1TSHRKDM4EMEN1CYP1A2 | |
| Sulfuric Acid SCHEMBL12484548 | 0.61 | LMNA (0.42) | ALDH1A1TSHRKDM4EMEN1CYP1A2 | |
| Sulfamate SCHEMBL7150762 | 0.58 | CA1 (0.53) | ALDH1A1TSHRKDM4EMEN1CYP1A2 | |
| Sulfuric Acid SCHEMBL8142689 | 0.58 | CYP1A2 (0.36) | TSHRKDM4ECYP1A2 | |
| Sulfuric Acid SCHEMBL4612293 | 0.58 | PDPK1 (0.34) | TSHRKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640630-B2 | Elastomeric composites containing modified fillers and functionalized elastomers | CABOT CORPORATION (US) | 2020-05-05 | — | — | US | disclosed |
| EP-2819854-B1 | ELASTOMERIC COMPOSITES CONTAINING MODIFIED FILLERS AND FUNCTIONALIZED ELASTOMERS | CABOT CORP (US) | 2020-04-15 | — | — | EP | disclosed |
| US-9175150-B2 | Modified carbon blacks having low PAH amounts and elastomers containing the same | CABOT CORPORATION (US) | 2015-11-03 | — | — | US | disclosed |
| US-20150183962-A1 | Elastomeric Composites Containing Modified Fillers And Functionalized Elastomers | CABOT CORPORATION (US) | 2015-07-02 | — | — | US | disclosed |
| US-8975316-B2 | Modified fillers and elastomeric composites comprising same | CABOT CORPORATION (US) | 2015-03-10 | — | — | US | disclosed |
| EP-2819854-A1 | ELASTOMERIC COMPOSITES CONTAINING MODIFIED FILLERS AND FUNCTIONALIZED ELASTOMERS | Cabot Corporation (US) | 2015-01-07 | — | — | EP | disclosed |
| WO-2013130099-A1 | ELASTOMERIC COMPOSITES CONTAINING MODIFIED FILLERS AND FUNCTIONALIZED ELASTOMERS | CABOT CORPORATION (US) | 2013-09-06 | — | — | WO | disclosed |
| WO-2013130772-A1 | MODIFIED CARBON BLACKS HAVING LOW PAH AMOUNTS AND ELASTOMERS CONTAINING THE SAME | CABOT CORPORATION (US) | 2013-09-06 | — | — | WO | disclosed |
| US-20130231423-A1 | Modified Carbon Blacks Having Low PAH Amounts And Elastomers Containing The Same | CABOT CORPORATION (US) | 2013-09-05 | — | — | US | disclosed |
| US-20130165560-A1 | Modified Fillers And Elastomeric Composites Comprising Same | CABOT CORPORATION (US) | 2013-06-27 | — | — | US | disclosed |
| WO-2012031183-A2 | MODIFIED FILLERS AND ELASTOMERIC COMPOSITES COMPRISING SAME | CABOT CORPORATION (US) | 2012-03-08 | — | — | WO | disclosed |