SCHEMBL1708565

SCHEMBL1708565

NC(=O)c1ccc2nonc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIA3 P42263 1/20 0.54
GRIA4 P48058 1/20 0.54
ENPP2 Q13822 2/20 0.50
ADORA3 P0DMS8 1/20 0.50
ADORA2A P29274 1/20 0.50
ADORA2B P29275 1/20 0.50
ADORA1 P30542 1/20 0.50
EPHX2 P34913 1/20 0.46
TAS1R3 Q7RTX0 1/20 0.46
TAS1R1 Q7RTX1 1/20 0.46
TAS1R2 Q8TE23 1/20 0.46
IP6K1 Q92551 1/20 0.45
PKM P14618 1/20 0.45
TSHR P16473 1/20 0.43
RIPK2 O43353 1/20 0.43
LCK P06239 1/20 0.41
KMT2A Q03164 1/20 0.41
CHEK2 O96017 1/20 0.41
FGFR1 P11362 1/20 0.41
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL548490 0.82 GRIA3 (0.56) GRIA3GRIA4ENPP2ADORA3ADORA2A
SCHEMBL2733233 0.80 GRIA3 (0.54) GRIA3GRIA4ENPP2ADORA3ADORA2A
Hydrochloric Acid SCHEMBL562597 0.80 GRIA3 (0.54) GRIA3GRIA4ENPP2ADORA3ADORA2A
SCHEMBL548652 0.80 GRIA3 (0.54) GRIA3GRIA4ENPP2ADORA3ADORA2A
SCHEMBL2834465 0.79 ADORA3 (0.61) GRIA3GRIA4ENPP2ADORA3ADORA2A
SCHEMBL2731867 0.76 ADORA3 (0.50) GRIA3GRIA4ENPP2ADORA3ADORA2A
SCHEMBL13689278 0.76 GAA (0.50) GRIA3GRIA4ENPP2ADORA3ADORA2A
SCHEMBL8237246 0.76 GRIA3 (0.50) GRIA3GRIA4ENPP2ADORA3ADORA2A
SCHEMBL1420530 0.76 ADORA3 (0.57) GRIA3GRIA4ENPP2ADORA3ADORA2A
SCHEMBL9731669 0.76 ADORA3 (0.50) GRIA3GRIA4ENPP2ADORA3ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260056191-A1 POLYMERS AND CONJUGATES COMPRISING THE SAME VENTANA MEDICAL SYSTEMS, INC. (US) 2026-02-26 US claimed
US-20240123045-A1 NONAUTOLOGOUS MULTI-STRESSED CANCER CELLS AND USES THEREOF FOR VACCINATING AND TREATING CANCERS BRENUS PHARMA (FR) 2024-04-18 US claimed
US-11079372-B2 Polymers and conjugates comprising the same VENTANA MEDICAL SYSTEMS, INC. (US) 2021-08-03 US claimed
EP-2686438-B1 A METHOD OF ANALYZING CHROMOSOMAL TRANSLOCATIONS AND A SYSTEM THEREFOR VENTANA MED SYST INC (US) 2018-04-18 EP claimed
EP-3201628-A2 POLYMERS AND CONJUGATES COMPRISING THE SAME Ventana Medical Systems, Inc. (US) 2017-08-09 EP claimed
US-20170205399-A1 POLYMERS AND CONJUGATES COMPRISING THE SAME VENTANA MEDICAL SYSTEMS, INC. 2017-07-20 US claimed
US-9562259-B2 Method of analyzing chromosomal inversions VENTANA MEDICAL SYSTEMS, INC. (US) 2017-02-07 US claimed
WO-2016050913-A2 POLYMERS AND CONJUGATES COMPRISING THE SAME VENTANA MEDICAL SYSTEMS, INC. (US) 2016-04-07 WO claimed
CN-103534359-A A method of analyzing chromosomal translocations and a system therefore VENTANA MED SYST INC 2014-01-22 CN claimed
EP-2539466-A1 CYTOGENIC ANALYSIS OF METAPHASE CHROMOSOMES Ventana Medical Systems, Inc. (US) 2013-01-02 EP claimed
EP-1368323-B1 PYRIMIDINE MATRIX METALLOPROTEINASE INHIBITORS WARNER LAMBERT CO (US) 2010-06-30 EP claimed
EP-1362033-B1 PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS WARNER LAMBERT CO (US) 2007-04-04 EP claimed
US-6936616-B2 Pyrimidine matrix metalloproteinase inhibitors WARNER-LAMBERT COMPANY (US) 2005-08-30 US claimed
JP-2004518723-A 2004-06-24 JP claimed
EP-1368323-A1 PYRIMIDINE MATRIX METALLOPROTEINASE INHIBITORS Warner-Lambert Company LLC (US) 2003-12-10 EP claimed
EP-1362033-A1 PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS Warner-Lambert Company LLC (US) 2003-11-19 EP claimed
US-20020161000-A1 Pyridine matrix metalloproteinase inhibitors WARNER-LAMBERT COMPANY 2002-10-31 US claimed
US-20020151555-A1 Pyrimidine matrix metalloproteinase inhibitors BARVIAN NICOLE CHANTEL (US) 2002-10-17 US claimed
WO-2002064568-A1 PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS WARNER-LAMBERT COMPANY LLC (US) 2002-08-22 WO claimed
WO-2002064571-A1 PYRIMIDINE MATRIX METALLOPROTEINASE INHIBITORS WARNER-LAMBERT COMPANY LLC (US) 2002-08-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260056191-A1 POLYMERS AND CONJUGATES COMPRISING THE SAME POLD1, POLL, INCENP GRIA3 3674/4885GRIA4 2966/4885ENPP2 1307/4885
US-20020161000-A1 Pyridine matrix metalloproteinase inhibitors MMP13, MMP3, MMP11 GRIA3 1776/4885GRIA4 2522/4885ENPP2 1535/4885
US-20020151555-A1 Pyrimidine matrix metalloproteinase inhibitors MMP13, MMP3, MMP11 GRIA3 2640/4885GRIA4 3605/4885ENPP2 2111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.