Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | FADS1 | O60427 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716544 | 0.84 | HTR2A (0.33) | P2RX7ALDH1A1MAPTMAPK1HTR2A | |
| SCHEMBL1707982 | 0.82 | FFAR1 (0.33) | P2RX7FFAR1CYP2C8S1PR1FADS1 | |
| SCHEMBL10010874 | 0.79 | FFAR1 (0.46) | FFAR1 | |
| SCHEMBL1708170 | 0.76 | SMN1; SMN2 (0.32) | FFAR1MAPTMAPK1 | |
| SCHEMBL1708078 | 0.74 | MAPT (0.34) | FFAR1ALDH1A1MAPTMAPK1 | |
| SCHEMBL1708059 | 0.73 | MAPT (0.35) | FFAR1ALDH1A1MAPTMAPK1 | |
| SCHEMBL9456143 | 0.73 | S1PR1 (0.42) | FFAR1S1PR1ACHEDRD2 | |
| SCHEMBL9455927 | 0.73 | S1PR1 (0.42) | FFAR1S1PR1ACHEDRD2 | |
| SCHEMBL1708366 | 0.73 | MAPT (0.34) | FFAR1ALDH1A1MAPTMAPK1 | |
| SCHEMBL1707749 | 0.71 | MAPT (0.34) | ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |