Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.35 |
| ▸ | FADS1 | O60427 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10010874 | 0.78 | FFAR1 (0.46) | FFAR1 | |
| SCHEMBL7406722 | 0.72 | DRD1 (0.41) | GAAL3MBTL1MAPTHTT | |
| SCHEMBL26789976 | 0.71 | FADS1 (0.46) | FADS1 | |
| SCHEMBL1707982 | 0.69 | FFAR1 (0.33) | FFAR1FADS1P2RX7CYP2C8 | |
| SCHEMBL7405122 | 0.68 | GAA (0.45) | FFAR1GAAL3MBTL1MAPTPTGDR2 | |
| SCHEMBL1881338 | 0.68 | GID4 (0.41) | HTTP2RX7 | |
| SCHEMBL22501405 | 0.68 | GID4 (0.41) | HTTP2RX7 | |
| SCHEMBL12474262 | 0.68 | FFAR1 (0.46) | FFAR1MAPT | |
| SCHEMBL1708702 | 0.67 | P2RX7 (0.35) | FFAR1FADS1MAPTP2RX7CYP2C8 | |
| SCHEMBL14567148 | 0.67 | FFAR1 (0.47) | FFAR1HTTPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |