Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17089973 | 0.90 | ALDH1A1 (0.47) | PKMHTTTP53MTNR1AMTNR1B | |
| SCHEMBL13565808 | 0.86 | LMNA (0.44) | PKMHTTLMNAMAPK1MTNR1A | |
| SCHEMBL10113580 | 0.86 | MAPK1 (0.49) | PKMHTTLMNAMAPK1TP53 | |
| SCHEMBL17090498 | 0.84 | PKM (0.47) | PKMHTTLMNAMAPK1PTGER2 | |
| SCHEMBL13565817 | 0.84 | THRB (0.46) | HTTLMNA | |
| SCHEMBL13565749 | 0.84 | MTNR1A (0.41) | PKMLMNAMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL13565730 | 0.84 | HDAC1 (0.44) | HTTMAPK1MTNR1AMTNR1B | |
| SCHEMBL13565422 | 0.83 | MTNR1A (0.40) | PKMLMNAMTNR1AMTNR1BNPC1 | |
| SCHEMBL13565431 | 0.82 | HSD17B10 (0.37) | PKMHTTLMNAMAPK1MTNR1A | |
| SCHEMBL7802434 | 0.82 | PPARA (0.62) | PKMHTTLMNAMAPK1PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |