Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.42 |
| ▸ | MGLL | Q99685 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17089975 | 0.84 | PTPN1 (0.47) | PTPN1MGLLPOLBKMT2ANOTUM | |
| SCHEMBL10113879 | 0.84 | MGLL (0.44) | PTPN1NPY5RMGLLPOLBKMT2A | |
| SCHEMBL17090341 | 0.84 | NPY5R (0.49) | NPY5RGRIA1MGLLPOLBKMT2A | |
| SCHEMBL10113740 | 0.78 | LMNA (0.49) | NPY5RMGLLPOLBKMT2AMAPT | |
| SCHEMBL17090102 | 0.76 | PTPN1 (0.44) | PTPN1MGLLPOLBKMT2ANOTUM | |
| SCHEMBL23460163 | 0.75 | PTPN1 (0.53) | PTPN1MGLLPOLBKMT2ANOTUM | |
| SCHEMBL11935057 | 0.73 | CHRM2 (0.66) | GRIA1KMT2APKMALDH1A1 | |
| SCHEMBL13565673 | 0.73 | GRIA1 (0.42) | NPY5RGRIA1HRH4HRH3 | |
| SCHEMBL13565350 | 0.72 | GRIA1 (0.50) | GRIA1KMT2AALDH1A1 | |
| SCHEMBL13565779 | 0.72 | HRH4 (0.50) | GRIA1HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |