Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 7/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17089983 | 0.84 | PTPN1 (0.45) | NPY5RGRIA1ALDH1A1MGLLPKM | |
| SCHEMBL17090338 | 0.84 | PKM (0.48) | NPY5RALDH1A1MGLLPKMNPC1 | |
| SCHEMBL10113740 | 0.84 | LMNA (0.49) | NPY5RALDH1A1MGLLPKMNPC1 | |
| SCHEMBL10113879 | 0.78 | MGLL (0.44) | NPY5RALDH1A1MGLLPKMNPC1 | |
| SCHEMBL13565845 | 0.77 | GRIA1 (0.54) | NPY5RGRIA1ALDH1A1PKMLMNA | |
| SCHEMBL13564802 | 0.77 | GRIA1 (0.54) | NPY5RGRIA1ALDH1A1PKMLMNA | |
| SCHEMBL13564968 | 0.76 | GRIA1 (0.59) | NPY5RGRIA1ALDH1A1PKMKMT2A | |
| SCHEMBL11935729 | 0.76 | GRIA1 (0.59) | NPY5RGRIA1ALDH1A1LMNARAB9A | |
| SCHEMBL17090446 | 0.75 | NPY5R (0.49) | NPY5RGRIA1 | |
| SCHEMBL13564814 | 0.74 | GRIA1 (0.58) | NPY5RGRIA1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |