Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 7/20 | 0.34 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.33 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090287 | 0.87 | GRIA1 (0.43) | CISD1NR3C1FABP4 | |
| SCHEMBL10115155 | 0.86 | ALDH1A1 (0.38) | FABP4KDM4EALDH1A1 | |
| SCHEMBL11935627 | 0.85 | LMNA (0.36) | KDM4EALDH1A1HTTPOLB | |
| SCHEMBL17090272 | 0.83 | ALDH1A1 (0.32) | CISD1FABP4ALDH1A1POLB | |
| SCHEMBL11935696 | 0.82 | ROCK1 (0.41) | KDM4EPLK1ALDH1A1HTT | |
| SCHEMBL11935634 | 0.79 | TAS1R3 (0.37) | FABP4ALDH1A1 | |
| SCHEMBL11935350 | 0.78 | BRD4 (0.38) | KDM4EALDH1A1 | |
| SCHEMBL17090273 | 0.76 | EPHX1 (0.32) | — | |
| SCHEMBL17090464 | 0.76 | LMNA (0.35) | NR3C1PLK1ALDH1A1HTT | |
| SCHEMBL10115111 | 0.74 | KDM4E (0.44) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |