Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090477 | 0.88 | PPARA (0.38) | GHSRALDH1A1EPHX2NR1H4LMNA | |
| SCHEMBL13565334 | 0.86 | ALDH1A1 (0.41) | GHSRALDH1A1EPHX2NR1H4LMNA | |
| SCHEMBL17090458 | 0.85 | GHSR (0.40) | GHSRALDH1A1EPHX2NR1H4LMNA | |
| SCHEMBL17090464 | 0.84 | LMNA (0.35) | GHSRALDH1A1EPHX2NR1H4LMNA | |
| SCHEMBL10116402 | 0.83 | LMNA (0.43) | ALDH1A1LMNACYP2C19ACLYKDM4E | |
| SCHEMBL13565371 | 0.80 | PTK2 (0.40) | GHSRALDH1A1EPHX2NR1H4LMNA | |
| SCHEMBL11936022 | 0.80 | ALOX5 (0.46) | ALDH1A1EPHX2LMNACYP1A2ALOX15 | |
| SCHEMBL11936037 | 0.78 | LMNA (0.42) | GHSRALDH1A1EPHX2NR1H4LMNA | |
| SCHEMBL17090059 | 0.77 | LMNA (0.40) | GHSRALDH1A1EPHX2NR1H4LMNA | |
| SCHEMBL17090272 | 0.76 | ALDH1A1 (0.32) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |