Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | ESRRA | P11474 | 1/20 | 0.33 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090459 | 0.88 | GHSR (0.35) | LMNAALDH1A1CYP1A2ALOX15CYP2C19 | |
| SCHEMBL17090485 | 0.84 | PPARA (0.41) | PPARAADRB2ADRB1ADRB3LMNA | |
| SCHEMBL17090505 | 0.83 | NR3C1 (0.39) | PPARAADRB2ADRB1ADRB3LMNA | |
| SCHEMBL10116707 | 0.83 | ACLY (0.40) | LMNAALDH1A1CYP2C19EPHX2NR1H4 | |
| SCHEMBL11936022 | 0.82 | ALOX5 (0.46) | LMNAALDH1A1CYP1A2ALOX15CYP2C19 | |
| SCHEMBL13566060 | 0.80 | PTK2 (0.41) | PPARALMNAALDH1A1CYP1A2ALOX15 | |
| SCHEMBL17090103 | 0.77 | ALDH1A1 (0.43) | PPARALMNAALDH1A1CYP1A2ALOX15 | |
| SCHEMBL13565069 | 0.77 | ALDH1A1 (0.53) | PPARALMNAALDH1A1CYP1A2ALOX15 | |
| SCHEMBL17090463 | 0.76 | LMNA (0.41) | PPARALMNAALDH1A1CYP1A2ALOX15 | |
| SCHEMBL11936085 | 0.75 | NAMPT (0.46) | PPARALMNAALDH1A1CYP1A2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |