Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.50 |
| ▸ | MEN1 | O00255 | 8/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10072039 | 0.82 | SCN9A (0.63) | ALDH1A1KMT2AMEN1NPSR1TSHR | |
| SCHEMBL1709235 | 0.80 | SCN9A (0.66) | ALDH1A1KMT2AMEN1TDP1NPSR1 | |
| SCHEMBL1286789 | 0.75 | HPGD (0.53) | ALDH1A1TSHRHPGDUSP2 | |
| Hydrochloric Acid SCHEMBL2023240 | 0.70 | POLB (0.76) | ALDH1A1KMT2AMEN1TDP1NPSR1 | |
| SCHEMBL1709223 | 0.70 | POLB (0.50) | ALDH1A1KMT2AMEN1TSHRSMN1; SMN2 | |
| SCHEMBL27008424 | 0.69 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1TSHRLMNA | |
| SCHEMBL4318899 | 0.69 | KCNQ2 (0.68) | ALDH1A1KMT2AMEN1TDP1NPSR1 | |
| SCHEMBL8142738 | 0.68 | NPSR1 (0.59) | ALDH1A1KMT2AMEN1TDP1NPSR1 | |
| SCHEMBL27008612 | 0.67 | GAA (0.44) | ALDH1A1TSHRLMNAHPGDHSD17B10 | |
| SCHEMBL27008550 | 0.67 | GAA (0.44) | ALDH1A1TSHRLMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047703-A2 | CYCLOPROPYL-SPIRO-PIPERIDINES USEFUL AS SODIUM CHANNEL BLOCKERS | SCHERING CORPORATION (US) | 2012-04-12 | — | — | WO | disclosed |