SCHEMBL17092974

SCHEMBL17092974

O=C(O)N1CCCC1Cc1ccccc1CC1CCCN1C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCD5 Q86SK9 1/20 0.45
DPP4 P27487 1/20 0.44
GABRA1 P14867 1/20 0.44
GABRG2 P18507 1/20 0.44
GABRB3 P28472 1/20 0.44
GABRA3 P34903 1/20 0.44
GABRA2 P47869 1/20 0.44
GABRB2 P47870 1/20 0.44
HRH3 Q9Y5N1 3/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
HSD11B1 P28845 1/20 0.43
FFAR1 O14842 2/20 0.43
PREP P48147 1/20 0.43
FAP Q12884 1/20 0.43
KCNH2 Q12809 1/20 0.43
HPGD P15428 1/20 0.42
CHRNB2 P17787 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3540701 0.91 ALDH1A1 (0.46) SCD5DPP4GABRA1GABRG2GABRB3
SCHEMBL908981 0.87 SCD5 (0.57) SCD5DPP4GABRA1GABRG2GABRB3
SCHEMBL23459127 0.87 SCD5 (0.57) SCD5DPP4GABRA1GABRG2GABRB3
SCHEMBL4964339 0.82 HSD11B1 (0.61) SCD5DPP4GABRA1GABRG2GABRB3
SCHEMBL4629395 0.82 HSD11B1 (0.61) SCD5DPP4GABRA1GABRG2GABRB3
SCHEMBL28618485 0.81 KMT2A (0.50) RAB9AMEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL29238125 0.81 HSD11B1 (0.60) SCD5DPP4GABRA1GABRG2GABRB3
SCHEMBL2397166 0.79 ALDH1A1 (0.43) DPP4NPC1RAB9AMEN1KMT2A
SCHEMBL15668142 0.78 DPP4 (0.47) DPP4FFAR1FAP
SCHEMBL15668139 0.78 DPP4 (0.47) DPP4FFAR1FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9670298-B2 Magnesium dichloride-ethanol adducts and catalyst component obtained therefrom BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2017-06-06 US disclosed
US-20150266981-A1 MAGNESIUM DICHLORIDE-ETHANOL ADDUCTS AND CATALYST COMPONENT OBTAINED THEREFROM BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2015-09-24 US disclosed